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13,14-dehydro-15-cyclohexyl Carbaprostacyclin
13,14-dehydro-15-cyclohexyl Carbaprostacyclin

Item number: Cay18212-500

13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.Formal Name:...
Keywords: 6,9alpha-methylene-11alpha-hydroxy-15,16,17,18,19,20-hexanor-14-(1-hydroxycyclohexyl)-prost-5E-en-13-yn-1-oic acid
Application: Bioactive lipid assays
CAS 145375-81-1
MW: 346.5 D
From 84.00€ *
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(±)5(6)-DiHET lactone
(±)5(6)-DiHET lactone

Item number: Cay51212-25

5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-delta-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring...
Keywords: (±)5,6-DiHETrE lactone, tetrahydro-6-[(3Z,6Z,9Z)-1-hydroxy-3,6,9-pentadecatrien-1-yl]-2H-pyran-2-one
Application: Bioactive lipid studies
CAS 213126-92-2
MW: 320.5 D
From 123.00€ *
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Leucomycin A13
Leucomycin A13

Item number: Cay28121-1

Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 µg/ml, respectively. It binds to ribosomes with an IC50 value of 1.2 µM in a...
Keywords: Kitasamycin A13, 4B-hexanoate leucomycin V
Application: Macrolide antibiotic
CAS 78897-52-6
MW: 800 D
From 324.00€ *
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(Z-IETD)2-Rh 110 (trifluoroacetate salt)
(Z-IETD)2-Rh 110 (trifluoroacetate salt)

Item number: Cay28212-1

(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8. Upon enzymatic cleavage by caspase-8, rhodamine 110 (Cay-19061) is released and its fluorescence can be used to quantify caspase-8 activity. Rhodamine 110 displays excitation/emission maxima of 496/520 nm, respectively.Formal Name:...
Keywords: (Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2,...
Application: Fluorogenic caspase-8 substrate
MW: 1515.5 D
163.00€ *
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Adenylate Cyclase Toxin from Bordetella pertussis (recombinant, frozen liquid)
Adenylate Cyclase Toxin from Bordetella pertussis...

Item number: Cay28211-50

Adenylate cyclase toxin is a virulence factor in B. pertussis. It is composed of an adenylate cyclase domain that binds calmodulin and an RTX hemolysin domain that contains a pore-forming domain, an activation domain with two lysine acylation sites, calcium binding repeats, and a C-terminal secretion signal. The...
Keywords: Adenylyl Cyclase Toxin
Application: Virulence factor, pertussis vaccine antibody quantification
649.00€ *
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SPHINX31
SPHINX31

Item number: Cay21582-1

SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1, IC50 = 5.9 nM). It is selective for SRPK1 over a panel of 50 kinases at a concentration of 1 µM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1), an SRPK1 substrate, in PC3 cells (EC50 = 360 nM) and...
Keywords: 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide
Application: SRPK1 inhibitor
CAS 1818389-84-2
MW: 507.5 D
From 50.00€ *
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ACE2-HRP Conjugate
ACE2-HRP Conjugate

Item number: Cay502182-100

ACE2-HRP Conjugate has been tested and formulated to work exclusively with Cayman's SARS-CoV-2 (B.1.1.7, Alpha Variant) Neutralizing Antibody SimpleDetect ELISA Kit (Cay-502180). Please visit SARS-CoV-2 (B.1.1.7, Alpha Variant) Neutralizing Antibody SimpleDetect ELISA Kit (Cay-502180) for the kit protocol,...
80.00€ *
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