S-(2-aminoethyl) Isothiourea is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the Ki values are 1.8, 2.1, and 0.59 µM, respectively.Formal Name: 2-aminoethyl carbamimidothioate, dihydrobromide. CAS Number: 56-10-0. Synonyms: Antiradon, NSC 22877. Molecular Formula: C3H9N3S . 2HBr....

DHR is a cell-permeable fluorogenic probe that is used as an indicator of intracellular peroxynitrite formation. It is oxidized by peroxynitrite to the highly fluorescent product rhodamine in vitro. Neither nitric oxide, superoxide, nor hydrogen peroxide alone appear to oxidize DHR. Formation of rhodamine can be...

alpha-Fetoprotein is a glycoprotein and member of the albuminoid gene family and is involved in extracellular transport, cell proliferation, and the immune response. It is composed of a single polypeptide chain with three domains that form a V shape, the inside of which comprises the ligand-binding domain, and...

kb NB 142-70 is a selective inhibitor of protein kinase D (PKD) with IC50 values of 28.3, 58.7, and 53.2 nM for PKD1, 2, and 3, respectively. It has been shown to inhibit prostate cancer cell migration and invasion, as well as reduce wound healing in vitro.Formal Name:...

1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 µM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name:...