4 products were found matching "Cay520111-%25"!

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SGI-7079
SGI-7079

Item number: Cay20111-25

SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 µM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib...
Keywords: 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-benzeneacetonitrile
Application: Axl inhibitor
CAS 1239875-86-5
MW: 455.5 D
From 43.00€ *
Review
Leukotriene B4 dimethyl amide
Leukotriene B4 dimethyl amide

Item number: Cay20115-25

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.Formal Name:...
Keywords: LTB4 dimethyl amide, N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenamide
Application: Bioactive lipid assays
CAS 83024-92-4
MW: 363.5 D
From 233.00€ *
Review
(±)5(6)-EET
(±)5(6)-EET

Item number: Cay50211-25

5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid (Cay-90010) by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-delta-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior...
Keywords: (±)5,6-EpETrE, (±)5,6-epoxy-8Z,11Z,14Z-eicosatrienoic acid
Application: Bioactive lipid assays
CAS 87173-80-6
MW: 320.5 D
From 61.00€ *
Review
8-CPT-Cyclic AMP (sodium salt)
8-CPT-Cyclic AMP (sodium salt)

Item number: Cay12011-25

8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 µM, respectively). 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase...
Keywords: 8-(p-Chlorophenylthio)-cAMP, 8-CPT-cAMP, 8-[(4-chlorophenyl)thio]-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium...
Application: PKA/PKG activator
CAS 93882-12-3
MW: 493.8 D
From 77.00€ *
Review