11 products were found matching "Cay519501"!

Cayman's 11-dehydro Thromboxane B2 (11-dehydro TXB2) ELISA Kit is a competitive assay that can be used for the quantification of 11-dehydro TXB2 in plasma, serum, urine, and other sample matrices. The assay has a range of 15.6-2,000 pg/ml, with a midpoint (50% B/B0) of 80-160 pg/ml, and a sensitivity (80% B/B0) of...

Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites within the receptor are being developed to preferentially target individual mGluR subtypes in order to determine...

L-Phenylalanine-13C6 is intended for use as an internal standard for the quantification of phenylalanine by GC- or LC-MS. L-Phenylalanine is an essential amino acid. Blood and brain levels of L-phenylalanine are increased and associated with progressive cognitive impairments, seizures, motor deficits, and autism in...

Ledipasvir is an inhibitor of hepatitis C virus (HCV) non-structural protein 5A (NS5A). It inhibits viral replication in genotype 1a and 1b HCV replicon cells (EC50s = 0.031 and 0.004 nM, respectively). It also inhibits viral replication in genotype 2a, 2b, 3a, 4a, 4d, 5a, 6a, and 6e HCV replicon cells (EC50s =...

Insulin is a polypeptide hormone with molecular weight of 6,000 Daltons, composed of two peptides chains, A and B, jointed by two cross-linked disulphide bonds and synthesised by the beta cells of the islets of Langherans of the pancreas. Insulin influences most of the metabolic functions of the body. Its best known...

ML-314 is a neurotensin-1 receptor (NTS1) agonist. It is selective for NTS1 over NTS2 in a cell-based assay of receptor/beta-arrestin complex formation (EC50s = 2 and >80 µM, respectively) but is inactive in an NTS1 calcium flux assay (EC50 = >80 µM) indicating that, in contrast to other NTS1 agonists, it does not...

Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K3 is a synthetic form of vitamin K that acts as a precursor to vitamin K2. It is capable of both redox cycling and arylating nucleophilic...

11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Cay-19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and beta-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon...

SKF 38393 is a partial agonist of the dopamine D1-like receptors D1 and D5 (Kis = 1 and ~0.5 nM, respectively). It less potently binds D2, D3, and D4 receptors (Kis = ~150, 5,000, and 1,000 nM, respectively).Formal Name: 2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol, monohydrobromide. CAS Number: 20012-10-6....

Cyproheptadine is an antihistamine with antiserotonergic and anticholinergic activities. It binds to histamine H1, muscarinic, and serotonin 5-HT2 receptors (Kis = 0.38, 1.26, and 0.83 nM, respectively, in radioligand binding assays). Cyproheptadine reduces histamine-induced spasms in isolated guinea pig ileum (IC75...

Chlorothricin is a macrolide-type antibiotic that inhibits pyruvate carboxylases from Bacillus, Azotobacter, rat, and chicken, preventing the conversion of pyruvate to oxaloacetate (Ki or IC50 = 173, 500, 260, and 120 µM, respectively). Chlorothricin also inhibits malate dehydrogenases MDH1 (cytoplasmic) and MDH2...