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Item number: Cay15190-25

The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation. CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM). It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2,...

Keywords:	CID-17253208, ML-249, N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide
Application:	Allosteric agonist of S1P3
CAS	945128-26-7
MW:	316.4 D

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