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(±)8(9)-DiHET
(±)8(9)-DiHET

Item number: Cay51351-25

(±)8(9)-DiHET is an oxylipin and a racemic mixture of the arachidonic acid metabolites 8(S),9(R)-DiHET and 8(R),9(S)-DiHET. It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) via an (±)8(9)-EET (Cay-50351) intermediate by epoxide hydrolases. (±)8(9)-DiHET (1 µM) induces cAMP production in...
Keywords: (±)8,9-DiHETrE, (±)8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid
Application: Bioactive lipid assays
CAS 192461-96-4
MW: 338.5 D
From 135.00€ *
Review
(±)14(15)-DiHET
(±)14(15)-DiHET

Item number: Cay51651-25

Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)14(15)-DiHET is the urinary metabolite of (±)14(15)-EET (Cay-50651) which has been documented by GC-MS to be elevated in pregnancy-induced hypertension.Formal Name:...
Keywords: (±)14,15-DiHETrE, (±)14,15-dihydroxy-5Z,8Z,11Z-eicosatrienoic acid
Application: Bioactive lipid studies
MW: 338.5 D
From 129.00€ *
Review
Gaboxadol (hydrochloride)
Gaboxadol (hydrochloride)

Item number: Cay16355-25

Gaboxadol is a GABAA receptor agonist whose potency varies depending on the receptor subunit composition (partial agonist at alpha1beta2gamma2 (ED50 = 143 µM), full agonist at alpha5 (ED50 = 28-129 µM), and super agonist at alpha4beta3delta (ED50 = 6 µM)). It also acts as an antagonist at rho1 GABAC receptors (IC50...
Keywords: THIP, 4,5,6,7-tetrahydro-isoxazolo[5,4-c]pyridin-3(2H)-one, monohydrochloride
Application: GABAA receptor agonist
CAS 85118-33-8
MW: 176.6 D
From 65.00€ *
Review