- Search results for Cay516011-%25
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3 products were found matching "Cay516011-%25"!
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Item number: Cay11601-25
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCalpha, PKCgamma, and PKCepsilon (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, induces apoptosis, and reduces proliferation of...
Keywords: | LY317615, 3-(1-methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione |
Application: | PKCbeta inhibitor |
CAS | 170364-57-5 |
MW: | 515.6 D |
From 115.00€
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Item number: Cay15011-25
(±)-Ibutilide is a class III antiarrhythmic agent. It inhibits the rapidly activating delayed-rectifier potassium current (IKr) in AT-1 myocytes with an IC50 value of 20 nM. (±)-Ibutilide also enhances the late inward sodium current (INa) and increases the action potential duration in isolated guinea pig ventricular...
Keywords: | U-70226E, N-[4-[4-(ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide, 2E-butenedioate (2:1) |
Application: | Potassium channel blocker |
CAS | 122647-32-9 |
MW: | 442.6 D |
From 114.00€
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Item number: Cay10611-25
ST1535 is an adenosine A2A receptor antagonist. It is selective for adenosine A2A over A1 receptors (Kis = 2.3 and 107 nM, respectively, in radioligand binding assays). ST1535 inhibits agonist-induced production of cAMP in CHO cells expressing adenosine A2A receptors (IC50 = 353 nM). In vivo, ST1535 (10 and 20...
Keywords: | 2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine |
Application: | Adenosine A2A receptor antagonist |
CAS | 496955-42-1 |
MW: | 272.3 D |
From 163.00€
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