5 products were found matching "Cay512021-%25"!

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(±)5(6)-DiHET lactone
(±)5(6)-DiHET lactone

Item number: Cay51212-25

5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-delta-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring...
Keywords: (±)5,6-DiHETrE lactone, tetrahydro-6-[(3Z,6Z,9Z)-1-hydroxy-3,6,9-pentadecatrien-1-yl]-2H-pyran-2-one
Application: Bioactive lipid studies
CAS 213126-92-2
MW: 320.5 D
From 123.00€ *
Review
Delta2-Doramectin
Delta2-Doramectin

Item number: Cay25120-1

Delta2-Doramectin is a doramectin degradation product formed by the reversible base-catalyzed isomerization of doramectin (Cay-19467).Formal Name: (4S)-25-cyclohexyl-2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-3,4-dihydro-avermectin A1a. CAS Number: 1987882-63-2. Molecular Formula: C50H74O14. Formula Weight:...
Keywords: (4S)-25-cyclohexyl-2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-3,4-dihydro-avermectin A1a
Application: Degradation product
CAS 1987882-63-2
MW: 899.1 D
From 272.00€ *
Review
SB 202190 (hydrochloride)
SB 202190 (hydrochloride)

Item number: Cay21201-25

SB 202190 is a potent, selective, and cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases such as...
Keywords: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol, monohydrochloride
Application: p38 MAP kinase inhibitor
CAS 350228-36-3
MW: 367.8 D
From 43.00€ *
Review
beta-Lapachone
beta-Lapachone

Item number: Cay15021-25

beta-Lapachone is a natural quinone with diverse anti-cancer and anti-inflammatory effects. It inhibits topoisomerase I at 25 µM and transglutaminase (IC50 = 5 µM). In cancer cells which overexpress NAD(P)H:quinone oxidoreductase, beta-lapachone is reduced to beta-lapachone hydroquinone, which generates reactive...
Keywords: ARQ 501, NSC 26326, NSC 629749, SL 11001, 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
Application: Topoisomerase I and transglutaminase inhibitor
CAS 4707-32-8
MW: 242.3 D
From 97.00€ *
Review
2-PMAP
2-PMAP

Item number: Cay21021-25

2-PMAP is an inhibitor of the production of amyloid precursor protein (APP) and amyloid-beta (Abeta) secretion. It reduces levels of APP and its intracellular C-terminal fragments alpha-CTF and beta-CTF in CHO APP751SW cells when used at a concentration of 10 µM. 2-PMAP also reduces secretion of Abeta (1-40) and...
Keywords: 2-[(2-pyridinylmethyl)amino]-phenol
Application: APP expression modulator
CAS 102212-26-0
MW: 200.2 D
From 43.00€ *
Review