11 products were found matching "Cay500341"!

Satratoxin G is a macrocyclic trichothecene mycotoxin that has been found in S. chartarum. It induces cleavage of caspase-3 and poly(ADP-ribose) polymerase (PARP) in HL-60 cells when used at a concentration of 40 nM and is cytotoxic to HepG2, Hep-2, Caco-2, A204, U937, and Jurkat cells (IC50s = 2.2-9.7 ng/ml)....

(+)-Cannabidiol (Cay-9003416) is an analytical reference standard categorized as a synthetic cannabinoid. It is an isomer of the non-psychoactive phytocannabinoid cannabidiol (Cay-90080, Cay-ISO60156). This product is intended for research and forensic applications.Formal Name:...

C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system. C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet. C22 Galactosylceramide has been found in postmortem hippocampus from patients with...

C22 Phytoceramide-d3 is intended for use as an internal standard for the quantification of C22 phytoceramide (Cay-9003464) by GC- or LC-MS. C22 Phytoceramide is a sphingolipid that has been found in Moro blood orange (C. sinensis) peels. It has also been found in primary human astrocytes. [Matreya, LLC. Catalog No....

C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts. C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation. C26 sphingomyelin has been used a component of...

C26:1 Sphingomyelin is a naturally occurring sphingolipid that has been found in human aqueous humor. [Matreya, LLC. Catalog No. 2139]Formal Name: (7S,25Z)-4-hydroxy-7-[(1R,2E)-1-hydroxy-2-hexadecen-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetratriacont-25-en-1-aminium, 4-oxide, inner salt. CAS Number:...

Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) and a non-selective COX inhibitor (IC50 = 20 nM for both COX-1 and COX-2). It prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases prostaglandin E2 (PGE2) levels in paw tissue in a mouse model of...

Aldosterone 21-sulfate is a metabolite of the steroid hormone aldosterone (Cay-15273). It reduces the sodium-to-potassium ratio in rat urine when administered at doses ranging from 10 to 100 µg, indicating mineralocorticoid activity that is less than 1% that of aldosterone.Formal Name:...

(±)9(10)-DiHOME is the diol form of (±)9(10)-EpOME (Cay-52400), a cytochrome P450-derived epoxide of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) also known as leukotoxin. It is formed from 9(10)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. It is toxic to Sf21 cells expressing sEH and to...

Cayman's PGE2 Express ELISA is a competitive assay that can be used for quantification of PGE2 in urine, plasma, serum, tissue homogenates, and culture media samples. The assay has a range of 15.6-2,000 pg/ml, a sensitivity (80% B/B0) of approximately 40 pg/ml, and a lower limit of detection (LLOD) of 11...

(±)11-HETE is an oxylipin formed non-enzymatically from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). Levels of (±)11-HETE are increased in an in vitro model of lipid peroxidation induced by ferrous ammonium sulfate (FAS) in rat brain homogenates. Levels are also increased in rat liver in an in vivo model...