20 products were found matching "Cay500155"!

Cayman's Annexin A1 (human) ELISA Kit is a sandwich assay which can be used to measure human annexin A1 in tissue culture media, serum and plasma. The standard curve spans the range of 0.20 - 20 ng/ml. Annexin A1 is a natural anti-inflammatory protein produced by neutrophils and monocytes. The glucocorticoid-induced...

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-03814735 is a reversible inhibitor of both Aurora A and B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activity assays. PF-03814735 also inhibits the kinases FLT1, FAK, TrkA, Met,...

4'-Methyl-N-methylhexanophenone (hydrochloride) (Cay-9001515) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.Formal Name: 2-(methylamino)-1-(4-methylphenyl)-1-hexanone, monohydrochloride. CAS Number: 2749391-59-9. Molecular Formula:...

ADB-PINACA (Cay-14763) is an analog of AKB48 (Cay-ISO00060), a synthetic cannabinoid recently identified in herbal products. ADB-PINACA isomer 1 is a regioisomer of ADB-PINACA. The physiological and toxicological properties of this compound have not been determined. This product is intended for research and forensic...

N1-Acetylspermidine is an acetyl derivative of spermidine (Cay-14918) that acts as a substrate for polyamine oxidase (PAO). In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including...

Cannabidivarinic acid (Cay-9001575) is an analytical reference material categorized as a phytocannabinoid. Cannabidivarinic acid has been found in strains of Cannabis. This product is intended for research and forensic applications.Formal Name:...

Bazedoxifene (acetate) is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERalpha (IC50 = 26 nM) and ERbeta (IC50 = 99 nM). Bazedoxifene (actetate) antagonizes 17beta-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as...

Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium hydrogen sulfide is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has...

Prostaglandin D2 (PGD2) is biosynthesized in the brain by a lipocalin-type PGD2 synthase where it acts in the CNS to promote sleep induction and lowering of body temperature. PGD2 is also the major eicosanoid product of mast cells and is synthesized in large quantities by a hematopoetic-type PGD synthase during...

Cercosporamide is a natural antifungal phytotoxin isolated from the Cercosporidium fungus, which infects the leaves of cassava plants. Its antifungal effect results from its selective and potent inhibition of fungal PKC-like 1 kinases (Pkc1), which are central to cell wall integrity (IC50 = 25 nM for Candida Pkc1)....

Luteoreticulin is a nitro-containing bacterial metabolite originally isolated from S. luteoreticuli. It has mosquitocidal activity against A. aegypti when used at a concentration of 6.25 mg/L and nematocidal activity against C. elegans.Formal Name:...

MN-25-2-methyl derivative is a cannabinoid (CB) receptor ligand with Ki values of 8 and 29 nM at the central CB1 receptor and peripheral CB2 receptor, respectively. This product is intended for forensic and research applications.Formal Name:...