- Search results for Cay45220-%25
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12 products were found matching "Cay45220-%25"!
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Item number: Cay40259-25
12-oxo Stearic acid is a saturated oxo fatty acid (SOFA) and metabolite of ricinoleic acid (Cay-10009369) that has been found in cow and goat milk. Dietary administration of 12-oxo stearic acid (0.25%) induces encephalomalacia in chicks fed a vitamin E-deficient diet.Formal Name: 12-oxo-octadecanoic acid. CAS...
Keywords: | 12-keto Octadecanoic Acid, 12-keto Stearic Acid, 12-oxo C18:0, 12-oxo Octadecanoic Acid, NSC 2103, 12-oxo-octadecanoic acid |
Application: | Ricinoleic acid metabolite, saturated oxo fatty acid (SOFA) |
CAS | 925-44-0 |
MW: | 298.5 D |
From 133.00€
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Item number: Cay42550-25
12(S)-HpEPE is an active metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed from EPA by 12-lipoxygenase (12-LO). 12(S)-HpEPE (0.3 and 1 µM) inhibits IL-1beta-induced increases in the levels of COX-2 in human pulmonary microvascular endothelial cells...
Keywords: | 12S-hydroperoxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid |
Application: | Bioactive lipid assays |
CAS | 103239-14-1 |
MW: | 334.5 D |
From 270.00€
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Item number: Cay44230-25
5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. It is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. 5(S)-HpETE (1 µM) mediates the induction of the proto-oncogene c-fos in TNF-stimulated TA1 cells.Formal Name:...
Keywords: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 71774-08-8 |
MW: | 336.5 D |
From 143.00€
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Item number: Cay40152-25
[Asp371]-Tyrosinase (369-377) is a naturally occurring tyrosinase antigen peptide. It is formed via post-translational modification of Asn371. [Asp371]-Tyrosinase (369-377) binds to MHC class I subtype HLA-A*0201-positive T2 cells (IC50 = 1.2 µg/ml) and induces lysis of HLA-A2.1-positive T2 cells incubated with...
Keywords: | [Asp370]-Tyrosinase (368-376), Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val,... |
Application: | Tyrosinase antigen peptide |
MW: | 1031.2 D |
From 34.00€
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Item number: Cay34520-25
tau-Fluvalinate is a pyrethroid acaricide. It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed in Xenopus oocytes (EC50 = 60 nM). It also induces tail currents in honeybee parasitic Varroa mite (V. destructor) Nav1 channels (VdNav1) expressed in Xenopus...
Keywords: | tau-Fluvalinate, N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine, cyano(3-phenoxyphenyl)methyl ester |
Application: | Pyrethroid acaricide |
CAS | 102851-06-9 |
MW: | 502.9 D |
From 48.00€
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Item number: Cay13224-50
Neurodazine induces neuronal differentiation in skeletal muscle cells. In mouse C2C12 myoblasts, neurodazine (2 µM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human...
Keywords: | 2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole |
Application: | Metabolic studies |
CAS | 937807-66-4 |
MW: | 456.9 D |
From 163.00€
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Item number: Cay25402-25
Micheliolide is a sesquiterpene lactone and derivative of parthenolide (Cay-70080) that has been found in M. champaca and has diverse biological activities. It is an irreversible activator of the pyruvate kinase M2 isoform (PKM2, EC50 = 6 nM) that decreases viability of HL-60 cells when used at concentrations...
Keywords: | 3aS,4,5,7,8,9R,9aS,9bS-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-azuleno[4,5-b]furan-2(3H)-one |
Application: | Bioactive sesquiterpene lactone, PKM2 activator |
CAS | 68370-47-8 |
MW: | 248.3 D |
From 43.00€
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Item number: Cay52400-25
(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. It has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome. Mitochondrial dysfunction is the main feature of (±)9(10)-EpOME cytotoxicity, which may be due...
Keywords: | (±)9,10-EODE, Coronaric Acid, Leukotoxin, (±)9,10-epoxy-12Z-octadecenoic acid |
Application: | Bioactive lipid studies |
MW: | 296.5 D |
From 52.00€
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Item number: Cay52450-25
(±)12(13)-EpOME is the 12,13-cis epoxide form of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). It is formed primarily via linoleic acid metabolism by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to (±)12(13)-EpOME production when pharmacologically induced....
Keywords: | (±)12,13-EODE, (±)-Vernolic Acid, Isoleukotoxin, (±)12(13)epoxy-9Z-octadecenoic acid |
Application: | Bioactive lipid studies |
MW: | 296.5 D |
From 52.00€
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Item number: Cay21450-25
(S)-MCPG is an antagonist of metabotropic glutamate receptors (mGluRs) and the active component of (±)-MCPG, which is selective for Group I and Group II mGluRs. (S)-MCPG inhibits motoneuron depolarization induced by 1-amino-1,3-dicarboxycyclopentane (ACPD) in neonatal rat spinal cord in vitro and ACPD-induced...
Keywords: | (+)-MCPG, (+)-alpha-methyl-4-Carboxyphenylglycine, (S)-alpha-methyl-4-Carboxyphenylglycine,... |
Application: | Non-selective group I/group II metabotropic glutamate receptor antagonist |
CAS | 150145-89-4 |
MW: | 209.2 D |
From 89.00€
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Item number: Cay15420-25
Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14alpha-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a...
Keywords: | NSC 169434, R 14889, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole, mononitrate |
Application: | Sterol 14alpha-demethylase inhibitor, Antifungal imidazole |
CAS | 22832-87-7 |
MW: | 479.1 D |
From 44.00€
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Item number: Cay35420-25
BDA-366 is an antagonist of the BH4 domain of the anti-apoptotic protein Bcl-2 (Ki = 3.3 nM). It is selective for Bcl-2 over Bcl-xL, Mcl-1, A1/Bfl-1, and Bcl-2 lacking the BH4 domain (Kis = >500, >500, >500, and 654.8 nM, respectively) but does bind to BH1-, BH2-, or BH3 domain-deficient Bcl-2 (Kis = 12.4, 7.6, and...
Keywords: | 1-[[(2S)-3-(diethylamino)-2-hydroxypropyl]amino]-4-[[(2S)-2-oxiranylmethyl]amino]-9,10-anthracenedione |
Application: | Bcl2-BH4 domain antagonist |
CAS | 1909226-00-1 |
MW: | 423.5 D |
From 48.00€
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