7 products were found matching "Cay390050"!

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Arachidonoyl Ethanolamide-d8
Arachidonoyl Ethanolamide-d8

Item number: Cay390050-100

Arachidonoyl ethanolamide-d8 (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain. It is...
Keywords: AEA-d8, Anandamide-d8, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide-5,6,8,9,11,12,14,15-d8
Application: Standard
CAS 924894-98-4
MW: 355.6 D
From 66.00€ *
Review
GSK963
GSK963

Item number: Cay39900-50

GSK963 is an inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK1). It is selective for RIPK1 with less than 50% inhibition of 339 kinases in a panel at 10 µM. Unlike the RIPK1 inhibitor necrostatin-1 (Cay-11658), GSK963 is inactive against indolamine-2,3-dioxygenase (IDO). GSK963 inhibits necroptosis...
Keywords: 1-[(5S)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-1-propanone
Application: RIPK1 inhibitor
CAS 2049868-46-2
MW: 230.3 D
From 111.00€ *
Review
Polysarcosine100
Polysarcosine100

Item number: Cay39050-5

Polysarcosine100 is an amine-functionalized hydrophilic polymer. Surface modification of liposomes with polysarcosine polymers between 10 and 100 units long have been used to increase circulation half-life.Formal Name: N-butyl-2-(methyl((methylamino)methyl)amino)acetamide. Synonyms: pSar100. Molecular Formula:...
Keywords: pSar100, N-butyl-2-(methyl((methylamino)methyl)amino)acetamide
Application: Amine-functionalized hydrophilic polymer, hydrophobicity-masking
From 34.00€ *
Review
Ferroptocide
Ferroptocide

Item number: Cay39005-10

Ferroptocide is an inhibitor of thioredoxin (Trx) and a derivative of pleuromutilin (Cay-19452). It inhibits Trx activity in ES-2 ovarian cancer cells when used at a concentration of 20 µM and is cytotoxic to ES-2 cells (IC50 = 1.6 µM). Ferroptocide (5 µM) induces ferroptosis in ES-2 cells, an effect that can be...
Keywords: (2S,3aS,4S,5R,7R,8S,8aS,9R)-octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,...
Application: Thioredoxin inhibitor
CAS 2505218-38-0
MW: 586.1 D
From 40.00€ *
Review
20-HETE-d6
20-HETE-d6

Item number: Cay390030-50

20-HETE-d6 contains six deuterium atoms at the 16, 16', 17, 17', 18 and 18' positions. It is intended for use as an internal standard for the quantification of 20-HETE (Cay-90030) by GC- or LC-MS. 20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral...
Keywords: 20-hydroxy Arachidonic Acid-d6, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18-d6 acid
Application: Standard
CAS 2548939-89-3
MW: 326.5 D
From 244.00€ *
Review
4-Methoxycinnamic Acid
4-Methoxycinnamic Acid

Item number: Cay39500-50

4-Methoxycinnamic acid is a phenolic acid with diverse biological activities. It reduces A. fumigatus biofilm formation when used at concentrations ranging from 0.4 to 3.2 mM. In vivo, 4-methoxycinnamic acid (80 mg/kg) reduces the number of dysplastic aberrant crypt foci and dysplastic liver cells in a rat model of...
Keywords: p-Methoxycinnamic Acid, para-Methoxycinnamic Acid, NSC 5303, NSC 623437, O-methyl-p-Coumaric Acid,...
Application: Bioactive phenolic acid
CAS 830-09-1
MW: 178.2 D
From 35.00€ *
Review
Lipid AX4
Lipid AX4

Item number: Cay39070-50

Lipid AX4 is an ionizable cationic lipid (pKa = 6.89) that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Administration of LNPs containing lipid AX4 and encapsulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant mRNA encoding the...
Application: Ionizable cationic lipid, LNP formation
CAS 2735814-23-8
MW: 1451.2 D
From 205.00€ *
Review