(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 9-HODE...

(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs...

Gossypetin is a flavonoid that has been found in H. sabdariffa and has diverse biological activities. It inhibits the MAP2K kinases MKK3 and MKK6 in a concentration-dependent manner, as well as induces apoptosis and cell cycle arrest at the G2 phase in KYSE-450 and KYSE-510 esophageal cancer cells when used at a...

N6-[(6-Aminohexyl)carbamoylmethyl]-ADP is an alkylated derivative of the nucleotide and ATP precursor ADP (Cay-16778, Cay-21121). N6-[(6-Aminohexyl)carbamoyl-methyl]-ADP, bound to agarose beads, can be phosphorylated via acetate kinase to ATP (Cay-14498). It has been biotinylated and conjugated to an...