7 products were found matching "Cay34720"!
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15(S)-HETE
Item number: Cay34720-25
15(S)-HETE is an active metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by 15-lipoxygenase 2 (15-LO-2) in macrophages, as well as the prostate, lung, and skin, but also by 15-LO-1 in airway epithelial cells, eosinophils, and reticulocytes....
| Keywords: | 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54845-95-3 |
| MW: | 320.5 D |
From 53.00€
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15(S)-HETE-d8
Item number: Cay334720-25
15(S)-HETE-d8 is intended for use as an internal standard for the quantification of 15(S)-HETE (Cay-34720) by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
| Keywords: | 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 84807-87-4 |
| MW: | 328.5 D |
From 238.00€
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15(S)-HETE-biotin
Item number: Cay34722-50
15(S)-HETE is a major arachidonic acid metabolite produced by the 15-lipoxygenase pathway. It has been characterized as a potent inhibitor of 5-lipoxygenase. The mechanism by which 15(S)-HETE acts as a leukotriene inhibitor is not clear. In studies with P-18 mast/basophil cells, it was shown that specific 15-HETE...
| Keywords: | 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraene-(2-biotinyl)hydrazide |
| Application: | Affinity binding |
| CAS | 1217461-45-4 |
| MW: | 560.8 D |
From 205.00€
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(±)-Marinopyrrole A
Item number: Cay34723-10
(±)-Marinopyrrole A is an alkaloid that has been found in Streptomyces and has antibacterial activity. It is active against methicillin-resistant S. aureus (MRSA, MIC50 = 0.375-0.75 µg/ml).Formal Name: 1,1'-(4,4',5,5'-tetrachloro[1,3'-bi-1H-pyrrole]-2,2'-diyl)bis[1-(2-hydroxyphenyl)-methanone. CAS Number:...
| Keywords: | 1,1'-(4,4',5,5'-tetrachloro[1,3'-bi-1H-pyrrole]-2,2'-diyl)bis[1-(2-hydroxyphenyl)-methanone |
| Application: | Antibacterial alkaloid |
| CAS | 1227962-62-0 |
| MW: | 510.2 D |
From 46.00€
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NVP-2
Item number: Cay34725-10
NVP-2 is an inhibitor of the Cdk9/cyclin T1 complex (IC50 = 50s = 0.584->10 µM), as well as over a panel of 468 kinases at 1 µM. NVP-2 (250 nM) inhibits the proliferation of, and induces apoptosis in, MOLT-4 human acute lymphoblastic leukemia cells.Formal Name:...
| Keywords: | 4-[[[5'-chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetra... |
| Application: | Cdk9/cyclin T1 complex inhibitor |
| CAS | 1263373-43-8 |
| MW: | 513.1 D |
From 60.00€
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1-(3-Chlorophenyl)biguanide (hydrochloride)
Item number: Cay34726-10
1-(3-Chlorophenyl)biguanide (m-CPBG) is an agonist of the serotonin (5-HT) receptor subtype 5-HT3. It selectively binds 5-HT3 over 5-HT1A and 5-HT2 receptors (Kis = 0.002, 10, and 10 µM, respectively) but also binds to high and low affinity sites on the dopamine transporter (DAT, IC50s = 0.4 and 34.8 µM,...
| Keywords: | m-Chlorophenylbiguanide hydrochloride, m-CPBG, meta-Chlorophenylbiguanide, meta-CPBG,... |
| Application: | 5-HT3 receptor agonist |
| CAS | 2113-05-5 |
| MW: | 248.1 D |
From 43.00€
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8Br-HA
Item number: Cay34728-10
8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT, IC50 = 0.12 µM). It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 µM, respectively).Formal Name: 2-((4-bromo-6-oxo-7,8,9,10-tetrahydro-6H-benzo[c]chromen-3-yl)oxy)-N-hydroxyacetamide. CAS Number:...
| Keywords: | 2-((4-bromo-6-oxo-7,8,9,10-tetrahydro-6H-benzo[c]chromen-3-yl)oxy)-N-hydroxyacetamide |
| Application: | FHIT inhibitor |
| CAS | 2937864-01-0 |
| MW: | 368.2 D |
From 115.00€
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