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Item number: Cay34215-25

(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. (±)5-HETE lactone is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM. The lactone is several times more potent than the linear...

Keywords:	(±)5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid, 1,5-lactone
Application:	5-LO inhibitor
CAS	73279-37-5
MW:	302.5 D

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