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(±)20-HDHA
(±)20-HDHA

Item number: Cay33750-25

(±)20-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)20-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.Formal Name:...
Keywords: (±)20-HDoHE, 20-hydroxy Docosahexaenoic Acid, (±)20-hydroxy-4Z,7Z,10Z,13Z,16Z,18E-docosahexaenoic acid
Application: Oxidative stress marker
CAS 90906-41-5
MW: 344.5 D
From 104.00€ *
Review
NIK SMI1
NIK SMI1

Item number: Cay37750-25

NIK SMI1 is an inhibitor of NF-kappaB-inducing kinase (NIK, Ki = 0.23 nM). It inhibits NF-kappaB activation in a reporter assay using HEK293 cells (IC50 = 34 nM). NIK SMI1 inhibits B cell activating factor-induced survival of isolated mouse splenic B cells (IC50 = 373 nM).Formal Name:...
Keywords: 6-[3-[2-[(3R)-3-hydroxy-1-methyl-2-oxo-3-pyrrolidinyl]ethynyl]phenyl]-4-methoxy-2-pyridinecarboxamide
Application: NIK inhibitor
CAS 1660114-31-7
MW: 365.4 D
From 77.00€ *
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(±)11-HEDE
(±)11-HEDE

Item number: Cay37500-25

(±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE (Cay-37510) and 11(R)-HEDE (Cay-37505). 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.Formal Name: 11-hydroxy-12E,14Z-eicosadienoic acid. CAS Number: 5598-37-8. Synonyms: 11-hydroxy-12,14-Eicosadienoic...
Keywords: (±)-11-hydroxy-12E,14Z-eicosadienoic acid
Application: Bioactive lipid studies
CAS 5598-37-8
MW: 324.5 D
From 60.00€ *
Review