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Amonafide
Amonafide

Item number: Cay31623-50

Amonafide is a DNA-intercalating topoisomerase II poison. It reduces the formation of kinetoplast DNA minicircles, a marker of topoisomerase II activity, in a cell-free assay at 100 µM, but does not induce relaxation of supercoiled DNA, a marker of topoisomerase I activity, at the same concentration. Amonafide...
Keywords: AS1413, Benzisoquinolinedione, Nafidimide, NCI 308847, NSC 308847,...
Application: Antineoplastic, DNA-intercalating topoisomerase II inhibitor
CAS 69408-81-7
MW: 283.3 D
From 68.00€ *
Review
YF-2
YF-2

Item number: Cay31230-25

YF-2 is a histone acetyltransferase (HAT) activator. It inhibits proliferation of CCRF-CEM, Hs 578T, A549, and U251 cancer cells (IC50s = 88.7-286 µM), as well as multidrug-resistant NCI/ADR-RES cells (IC50 = 44.8 µM). YF-2 (5 mg/kg) increases reduced acetylated histone H3 levels in a mouse of model of Alzheimer's...
Keywords: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxy-benzamide
Application: HAT activator
CAS 1311423-89-8
MW: 430.9 D
From 66.00€ *
Review
Surfactin
Surfactin

Item number: Cay31620-500

Surfactin is a cyclic lipopeptide biosurfactant produced by various strains of Bacillus. It is composed of a variable heptapeptide and a beta-hydroxy fatty acid that ranges in length from 12- to 15 carbons, which generates several isoforms. Surfactins interact with and destabilize biological membranes, resulting in...
Keywords: 3-((3S,6R,9S,12S,15R,18S,21S,25R)-9-(carboxymethyl)-3,6,15,18-tetraisobutyl-12-isopropyl-25-(10-methylundecyl)-2,5,8,11,14...
Application: Cyclic lipopeptide biosurfactant
CAS 252023-70-4
MW: 1036.3 D
From 250.00€ *
Review