tetranor-Prostaglandin E metabolite-d6 (tetranor-PGEM-d6) is intended for use as an internal standard for the quantification of tetranor-PGEM (Cay-14840) by GC- or LC-MS. tetranor-PGEM is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic...

G6PDi-1 is a reversible and noncompetitive inhibitor of glucose-6-phosphate dehydrogenase (G6PDH, IC50 = 0.07 µM), the enzyme that converts G6P to 6-phosphogluconolactone using NADP+ as a cofactor in the first step of the pentose phosphate pathway. G6PDi-1 (10 and 50 µM) reduces NADPH levels in a variety of cultured...