- Search results for Cay19500
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8 products were found matching "Cay19500"!
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Item number: Cay19500-50
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma level in human males...
Keywords: | 11-dehydro TXB2, 11-keto TXB2, 9alpha,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 67910-12-7 |
MW: | 368.5 D |
From 145.00€
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Item number: Cay11999-50
Olopatadine is a histamine H1 receptor antagonist (Ki =41 nM). It is 1,059- and 4,177-fold selective for histamine H1 over H2 and H3 receptors, respectively. Olopatadine inhibits histamine-induced phosphoinositide turnover in isolated human conjunctival epithelial cells, isolated human corneal fibroblasts, and human...
Keywords: | ALO 4943A, KW 4679, 11Z-[3-(dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid, monohydrochloride |
Application: | H1 histamine receptor antagonist |
CAS | 140462-76-6 |
MW: | 373.9 D |
From 50.00€
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Item number: Cay19550-1
ML-314 is a neurotensin-1 receptor (NTS1) agonist. It is selective for NTS1 over NTS2 in a cell-based assay of receptor/beta-arrestin complex formation (EC50s = 2 and >80 µM, respectively) but is inactive in an NTS1 calcium flux assay (EC50 = >80 µM) indicating that, in contrast to other NTS1 agonists, it does not...
Keywords: | 2-cyclopropyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)-1-piperazinyl]-quinazoline |
Application: | NTR1 agonist |
CAS | 1448895-09-7 |
MW: | 420.5 D |
From 56.00€
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Item number: Cay19503-10
SR 0987 is an agonist of the T cell-specific isoform of RORgamma (RORgammat, retinoic acid receptor-related orphan receptor-gammat), inducing reporter gene expression with an EC50 value of ~800 nM. Stimulation of mouse EL4 T lymphocytes with SR 0987, following activation with PMA (Cay-10008014) and ionomycin...
Keywords: | 2-chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzamide |
Application: | RORgammat agonist |
CAS | 303126-97-8 |
MW: | 397.7 D |
From 34.00€
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Item number: Cay19598-500
beta-Hydroxythiofentanyl-d5 (hydrochloride) (Cay-19598) is an analytical reference material intended for use as an internal standard for the quantification of beta-hydroxythiofentanyl (Cay-19736, Cay-17421) by GC- or LC-MS. beta-Hydroxythiofentanyl is categorized as an opioid. beta-Hydroxythiofentanyl-d5 is...
Keywords: | N-(1-(2-hydroxy-2-(thiophen-2-yl)ethyl)piperidin-4-yl)-N-phenylpropanamide-d5, monohydrochloride |
Application: | Analytical reference material, Opioid, GC-MS, LC-MS internal standard, Quantification |
CAS | 2747917-90-2 |
MW: | 400 D |
From 324.00€
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Item number: Cay19551-500
Cyproheptadine is an antihistamine with antiserotonergic and anticholinergic activities. It binds to histamine H1, muscarinic, and serotonin 5-HT2 receptors (Kis = 0.38, 1.26, and 0.83 nM, respectively, in radioligand binding assays). Cyproheptadine reduces histamine-induced spasms in isolated guinea pig ileum (IC75...
Keywords: | 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine, monohydrochloride, sesquihydrate |
Application: | H1-receptor antagonist |
CAS | 41354-29-4 |
MW: | 350.9 D |
From 50.00€
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Item number: Cay19580-100
9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a reagent used to detect singlet oxygen generation. This water-soluble derivative of anthracene can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease in...
Keywords: | ABMDMA, alpha9,alpha10-dicarboxy-9,10-anthracenedipropanoic acid |
Application: | Singlet oxygen detection |
CAS | 307554-62-7 |
MW: | 410.4 D |
From 105.00€
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Item number: Cay19524-500
4-Methylumbelliferyl 6-thio-palmitate-beta-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl...
Keywords: | Mu-6S-Palm-beta-Glc, 4-methyl-7-[[6-S-(1-oxohexadecyl)-6-thio-beta-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one |
Application: | Fluorogenic palmitoyl-protein thioesterase substrate |
CAS | 229644-17-1 |
MW: | 592.8 D |
From 64.00€
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