- Search results for Cay19027-%25
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8 products were found matching "Cay19027-%25"!
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Item number: Cay19057-25
Sodium oxamate is a derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis. Because cancer cells produce a large amount of energy via aerobic glycolysis, sodium oxamate has been studied as an inhibitor of carbohydrate metabolism in various...
Keywords: | Oxalic Acid monoamide, Oxamic Acid, 2-amino-2-oxo-acetic acid, monosodium salt |
Application: | Glycolysis disruptor, Lactate dehydrogenase inhibitor |
CAS | 565-73-1 |
MW: | 111 D |
From 80.00€
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Item number: Cay19067-25
Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA, Cay-90310) in macrophages. DHA is oxidized to maresin 1 (MaR1, Cay-10878), which is converted to MCTR1 (Cay-17007) by glutathione S-transferase Mu 4 or leukotriene C4...
Keywords: | 13-cysteinyl-14-hydroxy-Docosahexaenoic Acid, Maresin Conjugates in Tissue Regeneration 3, Maresin Sulfido Conjugate 3,... |
Application: | Specialized pro-resolving mediator (SPM) |
CAS | 1784701-63-8 |
MW: | 463.6 D |
From 184.00€
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Item number: Cay19087-25
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. HLY78 is a positive modulator of the Wnt/beta-catenin pathway, as it augments Wnt-mediated signaling in cells at concentrations of 5 to 20 µM. It has no significant effect alone, and it...
Keywords: | 4-ethyl-5,6-dihydro-5-methyl-[1,3]dioxolo[4,5-j]phenanthridine |
Application: | Wnt signaling modulator |
CAS | 854847-61-3 |
MW: | 267.3 D |
From 61.00€
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Item number: Cay12097-25
Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRalpha, PDGFRbeta, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional...
Keywords: | GSK-VEG10003, GW786034B, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
Application: | Broad spectrum tyrosine kinase inhibitor |
CAS | 444731-52-6 |
MW: | 437.5 D |
From 37.00€
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Item number: Cay11097-25
25-hydroxy Cholesterol is an oxysterol. It is formed from cholesterol by cholesterol-25-hydroxylase, and its production can be induced by inflammation or infection. 25-hydroxy Cholesterol suppresses endogenous cholesterol synthesis by binding to insulin-induced gene (INSIG) proteins and preventing sterol regulatory...
Keywords: | 25-OH Cholesterol, cholest-5-ene-3beta,25-diol |
Application: | Metabolic studies |
CAS | 2140-46-7 |
MW: | 402.7 D |
From 34.00€
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Item number: Cay17097-25
Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S,...
Keywords: | MBBr, NSC 608544, 3-(bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione |
Application: | Thiol-reactive fluorogenic probe |
CAS | 71418-44-5 |
MW: | 271.1 D |
From 60.00€
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Item number: Cay19073-25
Cantharidic acid is a hydrolysis product of cantharidin (Cay-14589), an inhibitor of protein phosphatases first isolated from Chinese blister beetles. Cantharidic acid inhibits the protein phosphatases PP1 and PP2A with IC50 values of 0.6 and 0.05 µM, respectively, but does not affect PP2B or PP2C. Cantharidic acid...
Keywords: | (1R,2S,3R,4S)-rel-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, disodium salt |
Application: | PP1 / PP2A inhibitor |
CAS | 1465-77-6 |
MW: | 258.2 D |
From 60.00€
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Item number: Cay19076-25
Nuclear retinoic acid receptors (RARs) are transcriptional regulators with roles in cell proliferation and differentiation. BMS 453 is a synthetic retinoid that acts as an agonist of RARbeta and an antagonist of RARalpha and RARgamma. It has been shown to inhibit the proliferation of normal breast cells via the...
Keywords: | BMS 189453, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl], benzoic acid |
Application: | RARbeta agonist, RARalpha / RARgamma antagonist |
CAS | 166977-43-1 |
MW: | 380.5 D |
From 50.00€
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