- Search results for Cay19023-%25
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8 products were found matching "Cay19023-%25"!
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Item number: Cay19083-25
NF-kappaB activation inhibitor III is an inhibitor of NF-kappaB activation. NF-kappaB activation inhibitor III (20 µM) inhibits TNF-alpha-induced NF-kappaB activation in HT-1080 fibrosarcoma cells. NF-kappaB activation inhibitor III inhibits TNF-alpha-induced expression of the gene encoding matrix...
Keywords: | SM-7368, 3-chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide |
Application: | MMP-9 protein expression inhibitor, NF-kappaB activition inhibitor |
CAS | 380623-76-7 |
MW: | 328.7 D |
From 119.00€
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Item number: Cay19093-25
BMI1/RING1A and BMI1/RNF2 are E3 ubiquitin ligase complexes that mediate the monoubiquitination of histone 2A (H2A). This is an essential function of polycomb repressive complex 1 (PRC1). PRT4165 is an inhibitor of the ubiquitin ligase activity of PRC1. It blocks BMI1/RING1A self-ubiquitination (IC50 = 3.9 µM), as...
Keywords: | NSC 600157, 2-(3-pyridinylmethylene)-1H-indene-1,3(2H)-dione |
Application: | BMI1/RING1A & BMI1/RNF2 inhibitor |
CAS | 31083-55-3 |
MW: | 235.2 D |
From 77.00€
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Item number: Cay19073-25
Cantharidic acid is a hydrolysis product of cantharidin (Cay-14589), an inhibitor of protein phosphatases first isolated from Chinese blister beetles. Cantharidic acid inhibits the protein phosphatases PP1 and PP2A with IC50 values of 0.6 and 0.05 µM, respectively, but does not affect PP2B or PP2C. Cantharidic acid...
Keywords: | (1R,2S,3R,4S)-rel-2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, disodium salt |
Application: | PP1 / PP2A inhibitor |
CAS | 1465-77-6 |
MW: | 258.2 D |
From 60.00€
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Item number: Cay10009023-25
(+)-WIN 55,212-2 (mesylate) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. In primary cultures of rat cerebral cortex neurons, (+)-WIN 55,212-2 (mesylate) (0.01-100 nM) increases extracellular glutamate...
Keywords: | [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone,... |
Application: | Aminoalkylindole CB receptor agonist |
CAS | 131543-23-2 |
MW: | 522.6 D |
From 62.00€
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Item number: Cay18093-25
The hepatocyte growth factor receptor c-Met commonly shows elevated activity in several forms of cancer. SGX523 is a potent, selective, ATP-competitive inhibitor that blocks the tyrosine kinase activity of c-Met with an IC50 value of 4 nM. It is over 1,000-fold selective for c-Met over a panel of other kinases....
Keywords: | 6-[[6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]-quinoline |
Application: | c-Met inhibitor |
CAS | 1022150-57-7 |
MW: | 359.4 D |
From 60.00€
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Item number: Cay13093-25
N-tridecanoyl-L-Homoserine lactone is an N-acyl homoserine lactone that has been found in Y. pseudotuberculosis.Formal Name: N-[(3S)-tetrahydro-2-oxo-3-furanyl]-tridecanamide. CAS Number: 878627-21-5. Synonyms: C13-HSL. Molecular Formula: C17H31NO3. Formula Weight: 297.4. Purity: >98%. Formulation: (Request...
Keywords: | C13-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-tridecanamide |
Application: | Bioactive lipid assays |
CAS | 878627-21-5 |
MW: | 297.4 D |
From 60.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15093-25
Phosphatidylethanolamines (PEs) are phospholipids found in biological membranes that serve both structural and functional roles. Different types of PE are commonly used in the generation of micelles, liposomes, and other types of artificial membranes. 1,3-Dipalmitoyl glycero-2-PE is a phospholipid containing the...
Keywords: | 1,3-DPPE, hexadecanoic acid, 1,1'-[2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1,3-propanediyl] ester |
Application: | Phospholipid |
CAS | 67303-93-9 |
MW: | 692 D |
From 66.00€
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Item number: Cay11093-25
Cannabinoids (CBs) and their synthetic analogs produce biochemical and pharmacological effects by interacting with the central CB1 and peripheral CB2 receptors. The CB2 receptor has emerged as a pharmacotherapeutic target for treating osteoporosis, as well as for eliciting antinociceptive effects in various models...
Keywords: | 4Q3C CB2 Ligand, 1,4-dihydro-8-methoxy-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-3-quinolinecarboxamide |
Application: | Forensic studies |
CAS | 1314230-69-7 |
MW: | 422.6 D |
From 48.00€
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