- Search results for Cay189542-%25
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8 products were found matching "Cay189542-%25"!
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Item number: Cay18924-25
ONO-4059 analog is a derivative of the Bruton's tyrosine kinase (BTK) inhibitor ONO-4059 (Cay-32957).Formal Name: 6-amino-7,9-dihydro-9-[(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one. CAS Number: 1351635-67-0. Synonyms: GS-4059 analog. Molecular Formula: C25H24N6O3. Formula Weight:...
Keywords: | GS-4059 analog, 6-amino-7,9-dihydro-9-[(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one |
Application: | BTK inhibitor |
CAS | 1351635-67-0 |
MW: | 456.5 D |
From 60.00€
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Item number: Cay18904-25
Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product prostaglandin H2 (PGH2, Cay-17020) into the biologically active PGE2 (Cay-14010). Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. PF-9184 is a potent inhibitor...
Keywords: | N-(3',4'-dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide |
Application: | mPGES-1 inhibitor |
CAS | 1221971-47-6 |
MW: | 461.3 D |
From 60.00€
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Item number: Cay18524-25
Corticotropin-releasing hormone, also known as corticotropin-releasing factor (CRF) or corticoliberin, is a peptide hormone and neurotransmitter involved in the stress response. It is secreted from the hypothalamus and is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion....
Keywords: | (7S)-6-(cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene,... |
Application: | CRF1 antagonist |
CAS | 603151-83-3 |
MW: | 497.4 D |
From 40.00€
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Item number: Cay18894-25
4,6-O-Benzylidene-D-glucose is a useful intermediate for the synthesis of carbohydrates.Formal Name: 4,6-O-(phenylmethylene)-D-glucose. CAS Number: 30688-66-5. Synonyms: 4,6-O-Benzylidene-D-glucopyranose. Molecular Formula: C13H16O6. Formula Weight: 268.3. Purity: >95%. Formulation: (Request formulation change), A...
Keywords: | 4,6-O-Benzylidene-D-glucopyranose, 4,6-O-(phenylmethylene)-D-glucose |
Application: | Carbohydrate synthesis intermediate |
CAS | 30688-66-5 |
MW: | 268.3 D |
From 58.00€
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Item number: Cay18495-25
Orexin receptors 1 (OX1R) and OX2R mediate the action of the neuropeptides orexin A and orexin B. TCS 1102 is a dual antagonist of both OX1R and OX2R (Kis = 0.2 and 3 nM, respectively). It is a poor substrate for P-glycoprotein and, as a result, demonstrates good brain penetration when administered...
Keywords: | (2S)-N-[1,1'-biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl]-2-pyrrolidinecarboxamide |
Application: | OX1R / OX2R antagonist |
CAS | 916141-36-1 |
MW: | 470.6 D |
From 43.00€
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Item number: Cay19584-25
1,7-Dimethyluric acid is a metabolite of caffeine (Cay-14118) produced by the action of xanthine oxidase on paraxanthine. It can be detected in urine as a biomarker of caffeine consumption.Formal Name: 7,9-dihydro-1,7-dimethyl-1H-purine-2,6,8(3H)-trione. CAS Number: 33868-03-0. Synonyms: 1,7-DMUA. Molecular Formula:...
Keywords: | 1,7-DMUA, 7,9-dihydro-1,7-dimethyl-1H-purine-2,6,8(3H)-trione |
Application: | Caffeine metabolite |
CAS | 33868-03-0 |
MW: | 196.2 D |
From 92.00€
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Item number: Cay21894-25
OSMI-1 is a quinolinone-6-sulfonamide that inhibits O-GlcNAc transferase (OGT, IC50 = 2.7 µM) in vitro. It is cell permeable and inhibits global O-GlcNAcylation in a dose-dependent manner in CHO cells. OSMI-1 induces a mass shift of nucleoporin62 (Nup62) that corresponds to the loss of O-GlcNAc residues and...
Keywords: | alphaR-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide |
Application: | OGT inhibitor |
CAS | 1681056-61-0 |
MW: | 563.6 D |
From 43.00€
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Item number: Cay19452-25
Pleuromutilin is an antibiotic derived from the fungus Clitopilus that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation.Formal Name: 2-hydroxy-acetic acid,...
Keywords: | Antibiotic A 40104C, Drosophilin B, NSC 121145, 2-hydroxy-acetic acid,... |
Application: | Antibiotic, Bacterial protein synthesis inhibitor |
CAS | 125-65-5 |
MW: | 378.5 D |
From 125.00€
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