9 products were found matching "Cay18900"!

Prostaglandin K2 (PGK2) is the 9,11-diketone formed by the oxidation of PGE2 or PGD2. Whether this compound exists biologically is uncertain, it is known to be resistant to metabolism by 15-hydroxy PGDH in vitro.Formal Name: 9,11-dioxo-15S-hydroxy-prosta-5Z,13E-dien-1-oic acid. CAS Number: 275816-51-8. Synonyms:...

A series of 2,5-phenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are 2,5-dimethoxy-4-substituted phenethylamines, many are regulated as illegal substances. 2C-N is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to...

D-Mannose-6-phosphate (M6P) is a phosphorylated aldohexose that has diverse physiological roles. It can be used to produce glucose as an energy source, converted to mannitol to serve as an osmolyte or metabolic store, or directed to the N-glycosylation pathway. M6P is also a ligand for both cation-dependent and...

DREADD agonist 21 activates hM3Dq (EC50 = 1.7 nM), a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor. It does not agonize the hM3 receptor and displays relatively weaker binding affinities for serotonin 5-HT2A, 5-HT2C, alpha1A-adrenergic,...

RB394 is an orally bioavailable, dual modulator of soluble epoxide hydrolase (sEH) and PPARgamma that inhibits sEH with an IC50 of 0.33 µM and activates PPARgamma with an EC50 of 0.3 µM. It is inactive at PPARdelta and shows 29% activation of PPARalpha, relative to control, at 10 µM. RB394 is water soluble, orally...

Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product prostaglandin H2 (PGH2, Cay-17020) into the biologically active PGE2 (Cay-14010). Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. PF-9184 is a potent inhibitor...

Prostaglandin E2 (PGE2, Cay-14010) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE2 during inflammation can be accounted for by increased...

Mitragynine-d3 (Cay-18929) is an analytical reference material intended for use as an internal standard for the quantification of mitragynine (Cay-11151, Cay-18567) by GC- or LC-MS. Mitragynine is categorized as an opioid. Mitragynine and its derivatives have been identified in products sold as incense. This product...

Zopiclone-d4 (Cay-18931) is intended for use as an internal standard for the quantification of zopiclone (Cay-14235) by GC- or LC-MS. Zopiclone is an analytical reference material categorized as a sedative. Zopiclone-d4 is regulated as a Schedule IV compound in the United States. This product is intended for...