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Ro 90-7501
Ro 90-7501

Item number: Cay18881-50

Ro 90-7501 is a bi-benzimidazole compound that was first found to retard the formation of mature amyloid beta42 fibrils in a cell-based assay. Instead, extended polymeric sheets and fibrillary intermediates of amyloid beta42 accumulated in response to Ro 90-7501 treatment, resulting in reduced cytotoxicity (EC50 = 2...
Keywords: 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Application: Abeta42 fibril assembly inhibitor, TLR3 signaling modulator
CAS 293762-45-5
MW: 340.4 D
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