16 products were found matching "Cay188150"!

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Anti-CD36   (Clone JC63.1)
Anti-CD36 (Clone JC63.1)

Item number: Cay188150-1

CD36, also known as scavenger receptor B2 or fatty acid translocase, is a transmembrane glycoprotein that has roles in fatty acid uptake and lipid metabolism and signaling. It is composed of N- and C-terminal cytoplasmic tails, two transmembrane domains, and an extracellular loop that binds to a variety of lipid...
Keywords: Anti-Cd36, Anti-GPIV, Anti-CD36, Anti-GPIV, Anti-CD36, Anti-PAS-4, Anti-PAS-4, Anti-GPIIIB, Anti-PAS IV, Anti-GPIIIB,...
Application: FC
Host: Mouse
Species reactivity: mouse
422.00€ *
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INK128
INK128

Item number: Cay11811-50

INK128 is an inhibitor of TORC1/2, acting as an ATP-dependent inhibitor of mTOR kinase (IC50 = 1 nM). It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors. Moreover, daily, oral...
Keywords: MLN0128, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application: TORC1/2 inhibitor
CAS 1224844-38-5
MW: 309.3 D
From 42.00€ *
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2-Trifluoromethyl-2'-methoxychalcone
2-Trifluoromethyl-2'-methoxychalcone

Item number: Cay11881-50

Nrf2 activation is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1. Because of its protective capabilities, small molecules that activate Nrf2...
Keywords: 1-(2-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-2E-propen-1-one
Application: Nrf2 activator
CAS 1309371-03-6
MW: 306.3 D
From 77.00€ *
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PF-CBP1
PF-CBP1

Item number: Cay18811-500

CREB-binding protein (CBP) and E1A-associated protein p300 are transcriptional co-activators that modulate DNA replication, DNA repair, cell growth, transformation, and development. Both CBP and p300 contain bromodomains, which mediate their binding to acetylated lysine residues on histones and other proteins....
Keywords: 5-(3,5-dimethyl-4-isoxazolyl)-1-[2-(4-morpholinyl)ethyl]-2-[2-(4-propoxyphenyl)ethyl]-1H-benzimidazole
Application: CBP/ p300 bromodomain inhibitor
CAS 1962928-21-7
MW: 488.6 D
From 43.00€ *
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Ro 90-7501
Ro 90-7501

Item number: Cay18881-50

Ro 90-7501 is a bi-benzimidazole compound that was first found to retard the formation of mature amyloid beta42 fibrils in a cell-based assay. Instead, extended polymeric sheets and fibrillary intermediates of amyloid beta42 accumulated in response to Ro 90-7501 treatment, resulting in reduced cytotoxicity (EC50 = 2...
Keywords: 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Application: Abeta42 fibril assembly inhibitor, TLR3 signaling modulator
CAS 293762-45-5
MW: 340.4 D
From 121.00€ *
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TBTA
TBTA

Item number: Cay18816-50

TBTA is a tertiary amine with three 1,2,3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry.Formal Name: tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine. CAS Number: 510758-28-8. Synonyms: Click Tag(TM) TBTA,...
Keywords: Tris(benzyltriazolylmethyl)amine, tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
Application: Azide-alkyne cycloaddition catalyst, click chemistry
CAS 510758-28-8
MW: 530.6 D
From 52.00€ *
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4'-fluoro-alpha-Pyrrolidinohexanophenone (hydrochloride)
4'-fluoro-alpha-Pyrrolidinohexanophenone (hydrochloride)

Item number: Cay18818-50

4'-fluoro-alpha-Pyrrolidinohexanophenone (hydrochloride) (Cay-18818) is an analytical reference material that is categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.Formal Name:...
Keywords: 4'-fluoro-Pyrrolidinohexanophenone, 4-fluoro-PHP, 4-fluoro-alpha-PHP, 1-(4-fluorophenyl)-2-(1-pyrrolidinyl)-1-hexanone,...
Application: Analytical reference material, Cathinone, Physiological/toxicological properties unknown
CAS 2748289-49-6
MW: 299.8 D
From 280.00€ *
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1-Methyl-4-imidazoleacetic Acid (hydrochloride)
1-Methyl-4-imidazoleacetic Acid (hydrochloride)

Item number: Cay18815-50

1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.Formal Name:...
Keywords: Methylimidazoleacetic Acid, MIAA, MIMA, 1-methyl-1H-imidazole-4-acetic acid, monohydrochloride
Application: Stable histamine metabolite
CAS 35454-39-8
MW: 176.6 D
From 56.00€ *
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Rosuvastatin (calcium salt)
Rosuvastatin (calcium salt)

Item number: Cay18813-50

Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the...
Keywords: (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoi...
Application: HMG-CoA reductase inhibitor
CAS 147098-20-2
MW: 500.6 D
From 43.00€ *
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2C-iP (hydrochloride)
2C-iP (hydrochloride)

Item number: Cay18281-50

2C-iP (hydrochloride) (Cay-18281) is an analytical reference standard that is classified as a phenethylamine. The physiological and toxicological properties of this compound have not been investigated. This product is intended for research and forensic applications.Formal Name:...
Keywords: 2-(4-isopropyl-2,5-dimethoxyphenyl)ethan-1-amine, monohydrochloride
Application: Analytical reference standard, Phenethylamine
CAS 1498978-47-4
MW: 259.8 D
From 291.00€ *
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Cyclic GMP (sodium salt)
Cyclic GMP (sodium salt)

Item number: Cay18821-50

Cyclic GMP (cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases. Activators of guanylate cyclases include nitric oxide and natriuretic peptides. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth...
Keywords: cGMP, Cyclic guanosine monophosphate, Guanosine 3'5'-cyclic monophosphate, Monosodium-GMP, cyclic 3',5'-(hydrogen...
Application: PKG activator
CAS 40732-48-7
MW: 367.2 D
From 84.00€ *
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Annexin A1 (human, recombinant)
Annexin A1 (human, recombinant)

Item number: Cay19881-50

Annexins are a superfamily of 13 proteins sharing a high degree of homology. They have in common a core C-terminal domain containing calcium and phospholipid binding motifs, allowing most of them to bind to phospholipid membranes in a calcium-dependent manner. The N-terminal domains vary between family members and...
Keywords: p35, p35, ANX1, ANXA1, Annexin I, Annexin-1, Annexin I, Annexin-1, Annexin A1, Annexin A1, Calpactin-2, Calpactin-2,...
Application: Bioassays
486.00€ *
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