9 products were found matching "Cay18230"!

Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. This modification increases the plasma half-life from 30 seconds to several hours, and permits the compound to be taken orally. Doses of 20-100 µg in humans, given 1 to 3 times per day, have been...

5alpha-Androst-16-en-3-one is a mammalian pheromone released as a volatile chemical cue in boar saliva to facilitate social and sexual interactions. It has been used to prime sexual behavior of sows in estrus for mating or artificial insemination. 5alpha-androst-16-en-3-one is also found in human sweat and urine and...

(S)-BAY-598 is a selective inhibitor of SMYD2. It inhibits the methylation of p53 at lysine 370 in vitro and in whole cells with IC50 values of 27 nM and Structural Genomics Consortium (SGC). The negative control, BAY-369, for (S)-BAY-598 is also available exclusively through the SGC. You can submit a request to...

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 µM), to destabilize microtubules and disrupt mitosis. At 50 µM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin...

Sucralfate is a gastrointestinal protectant that includes sucrose octasulfate (Cay-16382). Sucralfate protects gastric epithelial cells against acid- and pepsin-induced damage. Sucrose hexasulfate is a polysulfated disaccharide that is used as a reference standard for sucralfate.Formal Name:...

Deoxycholic acid (DCA) is a secondary bile acid that is formed via microbial transformation of cholic acid (Cay-20250) in the colon. It can be conjugated to glycine or taurine (Cay-27031) to produce glycodeoxycholic acid (GDCA, Cay-20274) or taurodeoxycholic acid (TDCA, Cay-15935), respectively, in hepatocytes. DCA...

Lansoprazole (Cay-13627) is a proton pump inhibitor that irreversibly inactivates the H+/K+-stimulated ATPase pumps in parietal cells, inhibiting gastric acid secretion and increasing intragastric pH. It is a 1:1 racemic mixture of (R)-lansoprazole and (S)-lansoprazole, both of which are pharmacologically active....

Pramipexole (Cay-11981) is an agonist of dopamine receptors that has applications in Parkinson's disease and other disorders. Pramipexole is usually available as a mixture of enantiomers, with the majority of the dopamine receptor-dependent activity resulting from the (S) form. (R)-Pramipexole is an enantiomer of...

2-Nitro-5-thiocyanatobenzoic acid is used to cyanylate proteins and to specifically cleave the amino-terminal peptide bond of cysteine residues.Formal Name: 2-nitro-5-thiocyanato-benzoic acid. CAS Number: 30211-77-9. Synonyms: NTCB. Molecular Formula: C8H4N2O4S. Formula Weight: 224.2. Purity: >98%. Formulation:...