3 products were found matching "Cay18228-%25"!
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PHA-767491 (hydrochloride)
Item number: Cay18218-25
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
| Keywords: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
| Application: | Cdc7 kinase inhibitor |
| CAS | 942425-68-5 |
| MW: | 249.7 D |
From 65.00€
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Ulixertinib (hydrochloride)
Item number: Cay18298-25
Ulixertinib is a reversible ERK1/2 inhibitor that demonstrates an IC50 value of V600E mutation, it has been reported to reduce the levels of phosphorylated ERK2 and the downstream kinase RSK (IC50s = 4.1 and 0.14 µM, respectively). Ulixertinib has also been shown to inhibit A375 cell proliferation with an IC50 value...
| Keywords: | BVD-523, VRT-752271,... |
| Application: | ERK1/ERK2 inhibitor |
| CAS | 1956366-10-1 |
| MW: | 469.8 D |
From 39.00€
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Mocetinostat
Item number: Cay18287-25
Mocetinostat is an orally available inhibitor of histone deacetylases (HDACs) that selectively targets HDAC1 and 2 (IC50s = 0.15 and 0.29 µM, respectively), less potently inhibits HDAC3 and 11 (IC50s = 1.66 and 0.59 µM, respectively) and has negligible actions against HDAC4-8. It induces hyperacetylation of...
| Keywords: | MGCD0103, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-benzamide |
| Application: | HDAC1 inhibitor |
| CAS | 726169-73-9 |
| MW: | 396.4 D |
From 60.00€
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