2 products were found matching "Cay18228"!

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Piriprost (potassium salt)
Piriprost (potassium salt)

Item number: Cay18228-10

Piriprost is a structural analog of prostaglandin I2 (PGI2) with low IP receptor-mediated activity. Piriprost inhibits 5-lipoxygenase with an IC50 around 100 µM, as measured by the release of 5-HETE from cultured myometrial cells. Piriprost inhibits the release of histamine and leukotrienes from isolated porcine...
Keywords: U-60257B, 1,4(R),5(R),6-tetrahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-1-phenyl-cyclopenta[b]pyrrole-2-pentanoic...
Application: Bioactive lipid assays
CAS 88851-62-1
MW: 463.7 D
From 72.00€ *
Review
MI-192
MI-192

Item number: Cay18288-1

MI-192 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC2 (IC50 = 30 nM) and HDAC3 (IC50 = 16 nM) over HDAC1, 4, 6, 7, and 8 (IC50s = 4.8, 5, >10, 4.1, and >10 µM, respectively). At 0.1-0.4 µM, it induces differentiation and promotes apoptosis of acute myeloid leukemic cell lines...
Keywords: N-(2-aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]-benzamide
Application: HDAC2/3 inhibitor
CAS 1415340-63-4
MW: 383.4 D
From 60.00€ *
Review