- Search results for Cay18228
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2 products were found matching "Cay18228"!
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Item number: Cay18228-10
Piriprost is a structural analog of prostaglandin I2 (PGI2) with low IP receptor-mediated activity. Piriprost inhibits 5-lipoxygenase with an IC50 around 100 µM, as measured by the release of 5-HETE from cultured myometrial cells. Piriprost inhibits the release of histamine and leukotrienes from isolated porcine...
Keywords: | U-60257B, 1,4(R),5(R),6-tetrahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-1-phenyl-cyclopenta[b]pyrrole-2-pentanoic... |
Application: | Bioactive lipid assays |
CAS | 88851-62-1 |
MW: | 463.7 D |
From 72.00€
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Item number: Cay18288-1
MI-192 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC2 (IC50 = 30 nM) and HDAC3 (IC50 = 16 nM) over HDAC1, 4, 6, 7, and 8 (IC50s = 4.8, 5, >10, 4.1, and >10 µM, respectively). At 0.1-0.4 µM, it induces differentiation and promotes apoptosis of acute myeloid leukemic cell lines...
Keywords: | N-(2-aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]-benzamide |
Application: | HDAC2/3 inhibitor |
CAS | 1415340-63-4 |
MW: | 383.4 D |
From 60.00€
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