2 products were found matching "Cay18216-%25"!
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Grazoprevir
Item number: Cay21816-5
Grazoprevir is a pan-genotypic protease inhibitor that binds to hepatitis C virus (HCV) non-structural protein 3/4A (NS3/4A), a serine protease essential for viral replication. Grazoprevir has potent in vitro activity against major HCV genotypes (Kis = 0.1, 0.1, 0.08, 0.15, and 0.9 nM for genotypes 1a, 1b, 2a, 2b,...
| Keywords: | MK-5172,... |
| Application: | HCV NS3/4A protease inhibitor |
| CAS | 1350514-68-9 |
| MW: | 766.9 D |
From 72.00€
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AEE788
Item number: Cay18416-25
AEE788 is an inhibitor of both epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) receptor tyrosine kinase family members. It can inhibit EGFR and VEGFR tyrosine kinases with IC50 values of 2, 6, 77, and 59 nM for EGFR, ErbB2, KDR, and FLT1, respectively. AEE788 demonstrates...
| Keywords: | NVP-AEE788, 6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Application: | EGFR & HER2/ErbB2 inhibitor |
| CAS | 497839-62-0 |
| MW: | 440.6 D |
From 52.00€
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