- Search results for Cay18215
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4 products were found matching "Cay18215"!
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Item number: Cay18215-1
Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated...
Keywords: | Ciloprost, 6,9alpha-methylene-11alpha,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid |
Application: | PGI analog |
CAS | 78919-13-8 |
MW: | 360.5 D |
From 92.00€
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Item number: Cay11821-5
Bacopaside I is a saponin that has been found in B. monniera and has diverse biological activities. It inhibits monoamine oxidase A (MAO-A) and MAO-B (IC50s = 17.08 and 94.22 µg/ml, respectively). Bacopaside I (5, 15, and 50 mg/kg) decreases immobility time in the tail suspension and forced swim tests, as well as...
Keywords: | (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl... |
Application: | Bioactive saponin |
CAS | 382148-47-2 |
MW: | 979.1 D |
From 98.00€
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Item number: Cay18218-5
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
Keywords: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
Application: | Cdc7 kinase inhibitor |
CAS | 942425-68-5 |
MW: | 249.7 D |
From 65.00€
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Item number: Cay18216-5
Ciprostene is the 9beta-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min. In addition, ciprostene...
Keywords: | Ciprostene calcium, U-61431F, 6,9alpha-methylene-9beta-methyl-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid,... |
Application: | Carbaprostacyclin analog |
CAS | 81703-55-1 |
MW: | 767.1 D |
From 204.00€
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