- Search results for Cay18212-%25
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5 products were found matching "Cay18212-%25"!
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Item number: Cay18218-25
Cdc7 kinase is a key regulator of the S-phase of the cell cycle. It is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent...
Keywords: | CAY10572, 1,5,6,7-tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrochloride |
Application: | Cdc7 kinase inhibitor |
CAS | 942425-68-5 |
MW: | 249.7 D |
From 65.00€
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Item number: Cay18271-25
Colony stimulating factor 1 (CSF1) is a cytokine that is involved in the recruitment and activation of tissue macrophages. It exerts these effects by binding to its corresponding receptor tyrosine kinase, the cFMS/CSF1 receptor (CSF1R). Pexidartinib is a brain-penetrant inhibitor of CSF1R, as well as c-Kit and FLT3...
Keywords: | PLX3397, N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine |
Application: | KIT / CSF1R / FLT3 inhibitor |
CAS | 1029044-16-3 |
MW: | 417.8 D |
From 84.00€
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Item number: Cay18231-25
Deoxycholic acid (DCA) is a secondary bile acid that is formed via microbial transformation of cholic acid (Cay-20250) in the colon. It can be conjugated to glycine or taurine (Cay-27031) to produce glycodeoxycholic acid (GDCA, Cay-20274) or taurodeoxycholic acid (TDCA, Cay-15935), respectively, in hepatocytes. DCA...
Keywords: | DCA, Sodium Deoxycholate, 5beta-3alpha,12alpha-dihydroxy-cholan-24-oic acid, monosodium salt, monohydrate |
Application: | Secondary bile acid |
CAS | 145224-92-6 |
MW: | 432.6 D |
From 43.00€
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Item number: Cay19281-25
S-Nitrosylation reactions regulate protein function and mediate nitrosative stress. S-Phenylsulfonylcysteine is a reagent for blocking thiol (-SH) groups on proteins and peptides at room temperature. This is the first step of the thiosulfonate switch technique, in which thiosulfonates are fluorescently tagged with a...
Keywords: | SPSC, S-(phenylsulfonyl)-L-cysteine |
Application: | Thiol group blocking reagent |
CAS | 97512-83-9 |
MW: | 261.3 D |
From 60.00€
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Item number: Cay14821-25
Cucurbitacin E is a plant-derived triterpene that has diverse biological activities. At a concentration of 10 pM, it reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro. Cucurbitacin E inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal...
Keywords: | NSC 106399, NSC 521775,... |
Application: | G2/M arrest inducer, Actin filament inducer |
CAS | 18444-66-1 |
MW: | 556.7 D |
From 56.00€
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