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PF-06463922
PF-06463922

Item number: Cay18371-10

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. PF-06463922 is an ATP-competitive, selective inhibitor of ALK (Ki = i = 0.7 nM). It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant...
Keywords: Lorlatinib,...
Application: ALK / ROS1 inhibitor
CAS 1454846-35-5
MW: 406.4 D
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