- Search results for Cay17020-%25
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4 products were found matching "Cay17020-%25"!
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Item number: Cay17010-25
Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key...
Keywords: | PGG2, 9alpha,11alpha-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 51982-36-6 |
MW: | 368.5 D |
From 119.00€
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Item number: Cay17080-25
Apcin is an inhibitor of the E3 ligase activity of the mitotic anaphase-promoting complex/cyclosome (APC/C). Apcin competitively binds to Cdc20 and prevents substrate interaction and ubiquitylation required for continuation of mitosis. Apcin enhances the effect of the APC/C inhibitor N-4-tosyl-L-arginine methyl...
Keywords: | [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-carbamic acid, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester |
Application: | Anaphase promoting complex inhibitor |
CAS | 300815-04-7 |
MW: | 438.7 D |
From 50.00€
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Item number: Cay17000-25
REV-ERBalpha is a nuclear receptor and transcription repressor that coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. SR8278 is an antagonist of REV-ERBalpha (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112 (Cay-11931). Moreover, SR8278 stimulates...
Keywords: | 1,2,3,4-tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid, ethyl ester |
Application: | NR1D1 antagonist |
CAS | 1254944-66-5 |
MW: | 361.5 D |
From 60.00€
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Item number: Cay17006-25
Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also...
Keywords: | ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione |
Application: | Microglial inhibitor |
CAS | 908568-01-4 |
MW: | 377.4 D |
From 179.00€
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