4 products were found matching "Cay17020-%25"!

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Prostaglandin G2
Prostaglandin G2

Item number: Cay17010-25

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key...
Keywords: PGG2, 9alpha,11alpha-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 51982-36-6
MW: 368.5 D
From 119.00€ *
Review
Apcin
Apcin

Item number: Cay17080-25

Apcin is an inhibitor of the E3 ligase activity of the mitotic anaphase-promoting complex/cyclosome (APC/C). Apcin competitively binds to Cdc20 and prevents substrate interaction and ubiquitylation required for continuation of mitosis. Apcin enhances the effect of the APC/C inhibitor N-4-tosyl-L-arginine methyl...
Keywords: [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-carbamic acid, 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester
Application: Anaphase promoting complex inhibitor
CAS 300815-04-7
MW: 438.7 D
From 50.00€ *
Review
SR8278
SR8278

Item number: Cay17000-25

REV-ERBalpha is a nuclear receptor and transcription repressor that coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. SR8278 is an antagonist of REV-ERBalpha (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112 (Cay-11931). Moreover, SR8278 stimulates...
Keywords: 1,2,3,4-tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid, ethyl ester
Application: NR1D1 antagonist
CAS 1254944-66-5
MW: 361.5 D
From 60.00€ *
Review
Inflachromene
Inflachromene

Item number: Cay17006-25

Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also...
Keywords: ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione
Application: Microglial inhibitor
CAS 908568-01-4
MW: 377.4 D
From 179.00€ *
Review