13 products were found matching "Cay17010"!

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Prostaglandin G2
Prostaglandin G2

Item number: Cay17010-25

Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key...
Keywords: PGG2, 9alpha,11alpha-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 51982-36-6
MW: 368.5 D
From 119.00€ *
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SR8278
SR8278

Item number: Cay17000-10

REV-ERBalpha is a nuclear receptor and transcription repressor that coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. SR8278 is an antagonist of REV-ERBalpha (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112 (Cay-11931). Moreover, SR8278 stimulates...
Keywords: 1,2,3,4-tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid, ethyl ester
Application: NR1D1 antagonist
CAS 1254944-66-5
MW: 361.5 D
From 60.00€ *
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Conessine
Conessine

Item number: Cay11700-100

Conessine is a steroidal alkaloid that has been found in H. antidysenterica and has diverse biological activities. It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis, S. aureus, M. luteus, and E. coli (MICs = 15.6-1,000 µg/disc in agar diffusion assays), the amoeba E....
Keywords: Neriine, NSC 119994, Roquessine, Wrightine, N,N-dimethyl-con-5-enin-3beta-amine
Application: Allergy/Asthma studies
CAS 546-06-5
MW: 356.6 D
From 161.00€ *
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GBR 12935 (hydrochloride)
GBR 12935 (hydrochloride)

Item number: Cay17700-100

GBR 12935 is an inhibitor of dopamine uptake that binds to the dopamine transporter (Kd = 27.2 nM). It is selective for the dopamine transporter over the serotonin and norepinephrine transporters (Kds = 940 and 310 nM, respectively). In mice, it increases locomotor activity, but not stereotypic behavior, when...
Keywords: 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-piperazine, dihydrochloride
Application: DAT & SLC6A2 inhibitor
CAS 67469-81-2
MW: 487.5 D
From 92.00€ *
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13(S),14(S)-epoxy Fluprostenol isopropyl ester
13(S),14(S)-epoxy Fluprostenol isopropyl ester

Item number: Cay11170-10

Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester (Cay-13679) is an impurity generated in the production of fluprostenol isopropyl ester....
Keywords: 13(S),14(S)-epoxy Travoprost, Epoxy Derivative 2, (Z)-isopropyl...
Application: FP receptor agonist
MW: 516.6 D
From 152.00€ *
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16F16
16F16

Item number: Cay17770-10

16F16 is a protein disulfide isomerase (PDI) inhibitor. It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 µg/ml. 16F16 reduces PC12 cell apoptosis induced by the misfolded huntingtin protein HTTQ103. It suppresses PDI-dependent mitochondrial outer membrane...
Keywords: 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylic acid, methyl ester
Application: PDI inhibitor
CAS 922507-80-0
MW: 320.8 D
From 53.00€ *
Review
Anti-Vitellogenin (sheepshead minnow)   (ND-5C9)
Anti-Vitellogenin (sheepshead minnow) (ND-5C9)

Item number: Cay170100-500

Immunogen: Vtg purified from sheepshead minnow (C. variegatus), bowfin (A. calva), brown bullhead (A. nebulosus), and spotted gar (L. oculatus). Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 M sodium azide....
Application: ELISA, WB
Host: Mouse
Species reactivity: Sheepshead minnow
From 385.00€ *
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KD 025
KD 025

Item number: Cay17055-10

KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...
Keywords: SLx-2119, 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide
Application: ROCK2 inhibitor
CAS 911417-87-3
MW: 452.5 D
From 75.00€ *
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SB-269970 (hydrochloride)
SB-269970 (hydrochloride)

Item number: Cay17081-10

The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-269970 is a potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6,...
Keywords: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-phenol, monohydrochloride
Application: 5-HT7A antagonist
CAS 261901-57-9
MW: 389 D
From 130.00€ *
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9-PAHPA
9-PAHPA

Item number: Cay17038-10

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a...
Keywords: 9-[(1-oxohexadecyl)oxy]-hexadecanoic acid
Application: FAHFA
CAS 1636134-70-7
MW: 510.8 D
From 84.00€ *
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Anti-Vitellogenin (striped bass)   (ND-3G2)
Anti-Vitellogenin (striped bass) (ND-3G2)

Item number: Cay170107-500

Immunogen: non-intact Vtg purified from plasma of 17beta-estradiol treated striped bass (M. saxatilis). Formulation: (Request formulation change), Purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 12.3 mM sodium azide, and 1% BSA. Host: Mouse. Applications: ELISA and WB. Origin:...
Application: ELISA, WB
Host: Mouse
Species reactivity: striped bass
From 385.00€ *
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Anti-Vitellogenin (striped bass)   (ND-1C8)
Anti-Vitellogenin (striped bass) (ND-1C8)

Item number: Cay170105-500

Immunogen: Vtg purified from plasma of 17beta-estradiol treated striped bass (M. saxatilis). Formulation: (Request formulation change), Purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 12.3 mM sodium azide, and 1% BSA. Host: Mouse. Applications: ELISA and WB. Origin: Animal/Mouse.
Application: ELISA, WB
Host: Mouse
Species reactivity: striped bass
From 385.00€ *
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