- Search results for Cay17010
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13 products were found matching "Cay17010"!
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Item number: Cay17010-25
Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2. Under normal conditions, PGG2 is quickly metabolized by the peroxidase activity intrinsic to both COX-1 and -2 to give PGH2, which serves as the key...
Keywords: | PGG2, 9alpha,11alpha-epidioxy-15S-hydroperoxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 51982-36-6 |
MW: | 368.5 D |
From 119.00€
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Item number: Cay17000-10
REV-ERBalpha is a nuclear receptor and transcription repressor that coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. SR8278 is an antagonist of REV-ERBalpha (EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112 (Cay-11931). Moreover, SR8278 stimulates...
Keywords: | 1,2,3,4-tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid, ethyl ester |
Application: | NR1D1 antagonist |
CAS | 1254944-66-5 |
MW: | 361.5 D |
From 60.00€
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Item number: Cay11700-100
Conessine is a steroidal alkaloid that has been found in H. antidysenterica and has diverse biological activities. It is active against a variety of Gram-positive and Gram-negative bacteria, including B. subtilis, S. aureus, M. luteus, and E. coli (MICs = 15.6-1,000 µg/disc in agar diffusion assays), the amoeba E....
Keywords: | Neriine, NSC 119994, Roquessine, Wrightine, N,N-dimethyl-con-5-enin-3beta-amine |
Application: | Allergy/Asthma studies |
CAS | 546-06-5 |
MW: | 356.6 D |
From 161.00€
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Item number: Cay17700-100
GBR 12935 is an inhibitor of dopamine uptake that binds to the dopamine transporter (Kd = 27.2 nM). It is selective for the dopamine transporter over the serotonin and norepinephrine transporters (Kds = 940 and 310 nM, respectively). In mice, it increases locomotor activity, but not stereotypic behavior, when...
Keywords: | 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-piperazine, dihydrochloride |
Application: | DAT & SLC6A2 inhibitor |
CAS | 67469-81-2 |
MW: | 487.5 D |
From 92.00€
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Item number: Cay11170-10
Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester (Cay-13679) is an impurity generated in the production of fluprostenol isopropyl ester....
Keywords: | 13(S),14(S)-epoxy Travoprost, Epoxy Derivative 2, (Z)-isopropyl... |
Application: | FP receptor agonist |
MW: | 516.6 D |
From 152.00€
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Item number: Cay17770-10
16F16 is a protein disulfide isomerase (PDI) inhibitor. It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 µg/ml. 16F16 reduces PC12 cell apoptosis induced by the misfolded huntingtin protein HTTQ103. It suppresses PDI-dependent mitochondrial outer membrane...
Keywords: | 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylic acid, methyl ester |
Application: | PDI inhibitor |
CAS | 922507-80-0 |
MW: | 320.8 D |
From 53.00€
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Item number: Cay170100-500
Immunogen: Vtg purified from sheepshead minnow (C. variegatus), bowfin (A. calva), brown bullhead (A. nebulosus), and spotted gar (L. oculatus). Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 M sodium azide....
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | Sheepshead minnow |
From 385.00€
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Item number: Cay17055-10
KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...
Keywords: | SLx-2119, 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide |
Application: | ROCK2 inhibitor |
CAS | 911417-87-3 |
MW: | 452.5 D |
From 75.00€
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Item number: Cay17081-10
The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-269970 is a potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6,...
Keywords: | 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-phenol, monohydrochloride |
Application: | 5-HT7A antagonist |
CAS | 261901-57-9 |
MW: | 389 D |
From 130.00€
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Item number: Cay17038-10
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a...
Keywords: | 9-[(1-oxohexadecyl)oxy]-hexadecanoic acid |
Application: | FAHFA |
CAS | 1636134-70-7 |
MW: | 510.8 D |
From 84.00€
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Item number: Cay170107-500
Immunogen: non-intact Vtg purified from plasma of 17beta-estradiol treated striped bass (M. saxatilis). Formulation: (Request formulation change), Purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 12.3 mM sodium azide, and 1% BSA. Host: Mouse. Applications: ELISA and WB. Origin:...
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | striped bass |
From 385.00€
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Item number: Cay170105-500
Immunogen: Vtg purified from plasma of 17beta-estradiol treated striped bass (M. saxatilis). Formulation: (Request formulation change), Purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 12.3 mM sodium azide, and 1% BSA. Host: Mouse. Applications: ELISA and WB. Origin: Animal/Mouse.
Application: | ELISA, WB |
Host: | Mouse |
Species reactivity: | striped bass |
From 385.00€
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