- Search results for Cay16920
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8 products were found matching "Cay16920"!
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Item number: Cay16920-100
19(R)-Hydroxylated prostaglandins (PGs) occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R). 19(R)-Hydroxylated PGs are also found in the seminal plasma of...
Keywords: | 15(R),19(R)-hydroxy PGF2alpha, 9alpha,11alpha,15R,19R-tetrahydroxy-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 1224444-23-8 |
MW: | 370.5 D |
From 53.00€
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Item number: Cay16929-10
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a turn-on fluorescent probe for hydrogen sulfide (H2S). Upon reaction with H2S, WSP-5 releases a fluorophore that...
Keywords: | Washington State Probe-5, 3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-(pyridin-2-yldisulfanyl)benzoate) |
Application: | Fluorescent probe, H2S detection |
CAS | 1593024-78-2 |
MW: | 822.9 D |
From 44.00€
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Item number: Cay16925-10
Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 is important for vascular development and lymphocyte maturation, migration, and trafficking. CYM...
Keywords: | 2-[[4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]amino]-ethanol |
Application: | S1PR1 internalization, phosphorylation, ubiquitination agonist |
CAS | 1094042-01-9 |
MW: | 409.5 D |
From 66.00€
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Item number: Cay16928-50
CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 µg/ml. It is without effect against MMP-1, MMP-9 or TNF-alpha converting enzyme. CL 82,198 is used to evaluate the role of MMP-13 in diverse processes, including cancer cell...
Keywords: | N-[4-(4-morpholinyl)butyl]-2-benzofurancarboxamide |
Application: | MMP-13 inhibitor |
CAS | 307002-71-7 |
MW: | 302.4 D |
From 84.00€
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Item number: Cay16922-10
Tenofovir disoproxil is a prodrug of the acyclic nucleoside phosphonate, tenofovir (Cay-13874). Tenofovir is converted by cellular enzymes to tenofovir diphosphate, an obligate chain terminator that inhibits the activity of HIV reverse transcriptase and hepatitis B virus polymerase. Due to its rapid intracellular...
Keywords: | Bis(POC)-PMPA, (5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic acid,... |
Application: | Antiviral prodrug |
CAS | 202138-50-9 |
MW: | 635.5 D |
From 84.00€
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Item number: Cay16924-10
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. alpha-Naphthoflavone is a flavone that modulates xenobiotic metabolism at...
Keywords: | 7,8-Benzoflavone, NSC 407011, 2-phenyl-4H-naphtho[1,2-b]pyran-4-one |
Application: | AhR expression modulator |
CAS | 604-59-1 |
MW: | 272.3 D |
From 39.00€
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Item number: Cay16926-250
Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan (Cay-29600). It is formed via sulfation of indoxyl, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor...
Keywords: | 3-(hydrogen sulfate), 1H-indol-3-ol, monopotassium salt |
Application: | Tryptophan metabolite |
CAS | 2642-37-7 |
MW: | 251.3 D |
From 50.00€
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Item number: Cay16923-250
Clinafloxacin is a fluoroquinolone antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).Formal Name:...
Keywords: | AM1091, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
Application: | Antibacterial antibiotic, DNA gyrase inhibitor, Topoisomerase IV inhibitor |
CAS | 105956-99-8 |
MW: | 402.3 D |
From 125.00€
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