- Search results for Cay16860
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6 products were found matching "Cay16860"!
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Item number: Cay16860-1
Swainsonine is an indolizidine alkaloid naturally found in certain plants including locoweed that inhibits N-linked glycoside hydrolases, preventing the processing of asparagine-linked glycoproteins. It reversibly inhibits lysosomal alpha-mannosidase and Golgi alpha-mannosidase II (IC50 = 0.2 µM). Swainsonine is...
Keywords: | Tridolgosir, (1S,2R,8aR)-octahydro-indolizinetriol |
Application: | N-linked glycoside hydrolase inhibitor |
CAS | 72741-87-8 |
MW: | 173.2 D |
From 74.00€
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Item number: Cay16867-50
m-3M3FBS is an activator of phospholipase C (PLC) that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 µM. It stimulates cytoplasmic calcium increases in several cell lines and, at 25 µM in vitro, promotes...
Keywords: | 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide |
Application: | PLC activator |
CAS | 200933-14-8 |
MW: | 343.4 D |
From 66.00€
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Item number: Cay16866-10
Coenzyme Q9 (CoQ9) is a mitochondrial ubiquinone with a role in the electron transport chain. It reduces the incidence of ischemia and reperfusion-induced arrhythmia and improves post-ischemic heart rate, coronary flow, aortic flow, and left ventricular developed pressure in isolated guinea pig hearts when used at a...
Keywords: | CoQ9, NSC 226993, Ubiquinone Q9, Ubiquinone-9,... |
Application: | Ubiquinone |
CAS | 303-97-9 |
MW: | 795.2 D |
From 60.00€
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Item number: Cay16868-50
N-nonanoyl-L-Homoserine lactone is an N-acylated homoserine lactone and a bacterial quorum-sensing signaling molecule. It induces GFP production in an E. coli reporter strain expressing the V. fischeri LuxR-PluxI quorum-sensing operon when used at concentrations ranging from 100 to 1,000 nM.Formal Name:...
Keywords: | C9-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-nonanamide |
Application: | Bioactive lipid assays |
CAS | 177158-21-3 |
MW: | 241.3 D |
From 50.00€
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Item number: Cay16861-10
Cycloguanil is the active metabolite of the antimalarial prodrug proguanil. Cycloguanil is formed from proguanil by the cytochrome P450 (CYP) isoforms CYP2C19 and CYP3A in human liver microsomes. It is an inhibitor of dihydrofolate reductase (DHFR, Kis = 1.5 and 0.79 nM for the P. falciparum and P. berghei enzymes,...
Keywords: | Chloroguanide Triazine, NSC 3074, 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine, monohydrochloride |
Application: | DHFR inhibitor |
CAS | 152-53-4 |
MW: | 288.2 D |
From 43.00€
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Item number: Cay16862-10
Ximelagatran is an ester prodrug of melagatran, a potent, direct, and reversible thrombin inhibitor (Ki = 1.2 nM). While melagatran has poor oral bioavailability, ximelagatran displays good bioavailability resulting, in part, from rapid absorption at the gastrointestinal tract, as well as rapid onset of action....
Keywords: | Exanta, H 376/95,... |
Application: | Melagatran prodrug, thrombin inhibitor |
CAS | 192939-46-1 |
MW: | 473.6 D |
From 47.00€
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