6 products were found matching "Cay16835-%25"!
No results were found for the filter!
beta-Carotene
Item number: Cay16837-25
beta-Carotene is a red/orange-colored fat-soluble terpenoid with antioxidant properties. It can be enzymatically cleaved to produce vitamin A and retinoic acid. Vitamin A is important for vision and bone growth, while retinoic acid, through the retinoic acid receptor, plays an important role in cell...
| Keywords: | Food Orange 5, KPMK, Lucarotin, NSC 62794, Provatene, Provitamin A, Solatene, beta,beta-carotene |
| Application: | Antioxidant |
| CAS | 7235-40-7 |
| MW: | 536.9 D |
From 66.00€
*
CAY10581
Item number: Cay16838-25
The enzyme indoleamine 2,3-dioxygenase (IDO) has been implicated in mediating pathological immunosuppression associated with certain diseases, including cancer. Several naphthoquinones inhibit IDO in vitro and in cells, but at low (µM) potency. Importantly, naphthoquinones reduce tumor growth in wild type mice but...
| Keywords: | (±)3,4-dihydro-3-hydroxy-2,2-dimethyl-4-[(phenylmethyl)amino]-2H-naphtho[2,3-b]pyran-5,10-dione |
| Application: | Indoleamine 2,3-dioxygenase inhibitor |
| CAS | 1018340-07-2 |
| MW: | 363.4 D |
From 50.00€
*
SR 11302
Item number: Cay16338-25
SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE. It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 µM). SR 11302 is used to elucidate the role of AP-1 in various signaling...
| Keywords: | (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid |
| Application: | AP-1 inhibitor |
| CAS | 160162-42-5 |
| MW: | 376.5 D |
From 60.00€
*
trans-Clovamide
Item number: Cay16138-25
trans-Clovamide is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.). It has antioxidant and antiradical properties and has shown neuroprotective effects (EC50s = 0.9-3.7 µM) in several in vitro models of neuronal death.Formal Name:...
| Keywords: | N-trans-Caffeoyl-L-DOPA, N-[3',4'-Dihydroxy-(E)-cinnamoyl]-3-hydroxy-L-tyrosine,... |
| Application: | Antioxidant |
| CAS | 53755-02-5 |
| MW: | 359.3 D |
From 127.00€
*
BIX02188
Item number: Cay16238-25
BIX02188 is a potent inhibitor of MEK5 (IC50 = 4.3 nM) with reduced activity towards inhibition of ERK5 and TGFbetaR1 (IC50s = 810 and 1,800 nM, respectively). It does not inhibit the closely related kinases MEK1, MEK2, ERK2, and JNK2 (IC50s = > 6,300 nM). BIX02188 inhibits phosphorylation of ERK5 in a...
| Keywords: | (3Z)-3-[[[3-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide |
| Application: | MEK5 inhibitor |
| CAS | 334949-59-6 |
| MW: | 412.5 D |
From 60.00€
*
Tomatidine (hydrochloride)
Item number: Cay16938-25
Tomatidine is a steroidal alkaloid that has been found in the skins and leaves of tomatoes. It suppresses NF-kappaB signaling in LPS-stimulated macrophages, blocking induced expression of inducible nitric oxide synthase (iNOS) and COX-2. Tomatidine inhibits acid sphingomyelinase activity by 84.2% when used at a...
| Keywords: | (3beta,5alpha,22beta,25S)-spirosolan-3-ol, monohydrochloride |
| Application: | Steroidal alkaloid |
| CAS | 6192-62-7 |
| MW: | 452.1 D |
From 48.00€
*