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Clozapine N-oxide
Clozapine N-oxide

Item number: Cay16882-25

Clozapine-N-oxide is a major metabolite of clozapine (Cay-12059) and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively). It...
Keywords: CNO, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
Application: Clozapine metabolite
CAS 34233-69-7
MW: 342.8 D
From 48.00€ *
Review
P7C3
P7C3

Item number: Cay16682-25

P7C3 is an orally bioavailable and brain penetrant aminopropyl carbazole that exhibits proneurogenic and neuroprotective activity by preventing apoptosis of newly postmitotic neurons in the subgranular zone of the hippocampal dentate gyrus. At doses of 5 mg/kg and above, it has been shown to promote the survival of...
Keywords: 3,6-dibromo-alpha-[(phenylamino)methyl]-9H-carbazole-9-ethanol
Application: Neuroprotective
CAS 301353-96-8
MW: 474.2 D
From 141.00€ *
Review