- Search results for Cay16821-%25
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6 products were found matching "Cay16821-%25"!
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Item number: Cay16871-25
Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. LPS is composed of polysaccharides and lipid A, where lipid A is a phosphoglycolipid containing acyl chains composed of 10 to 16 carbons. The lipid A component of LPS is detected by Toll-like receptor 4 of mammalian leukocytes and,...
Keywords: | 3(R)-hydroxy Tetradecanoic Acid, 3R-hydroxy-tetradecanoic acid |
Application: | Lipid A component |
CAS | 28715-21-1 |
MW: | 244.4 D |
From 131.00€
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Item number: Cay16891-25
GSK690693 is an ATP-competitive, pan-Akt kinase inhibitor with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively. It also inhibits other members of the AGC kinase family, including AMPK, DAPK3, PAKs, PKA, PKC, PKG, and PrkX (IC50 values range from 2-81 nM). By preventing the phosphorylation of...
Keywords: | 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-... |
Application: | Akt kinase inhibitor |
CAS | 937174-76-0 |
MW: | 425.5 D |
From 66.00€
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Item number: Cay16861-25
Cycloguanil is the active metabolite of the antimalarial prodrug proguanil. Cycloguanil is formed from proguanil by the cytochrome P450 (CYP) isoforms CYP2C19 and CYP3A in human liver microsomes. It is an inhibitor of dihydrofolate reductase (DHFR, Kis = 1.5 and 0.79 nM for the P. falciparum and P. berghei enzymes,...
Keywords: | Chloroguanide Triazine, NSC 3074, 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine, monohydrochloride |
Application: | DHFR inhibitor |
CAS | 152-53-4 |
MW: | 288.2 D |
From 43.00€
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Item number: Cay11861-25
Brefeldin A (BFA) is a natural fungal metabolite which has been used extensively to study intracellular transport by vesicles or endosomes. Early studies demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. BFA directly and...
Keywords: | Ascotoxin, BFA, Cyanein, Decumbin, Nectrolide, NSC 107456, NSC 244390, NSC 56310, NSC 89671, Synergisidin,... |
Application: | Endosomal trafficking studies |
CAS | 20350-15-6 |
MW: | 280.4 D |
From 46.00€
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Item number: Cay13861-25
Fmoc-Succinimide (Fmoc-OSu) is a mixed carbamate reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxyamino acids and hydroxyamino acid esters in high yields. Fmoc-OSu is a more preferable alternative to the use of the chloroformate, Fmoc-Cl, because it eliminates the...
Keywords: | FMOC-OSu, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 2,5-dioxo-1-pyrrolidinyl 9H-fluoren-9-ylmethyl ester-carbonic acid |
Application: | Chemical synthesis |
CAS | 82911-69-1 |
MW: | 337.3 D |
From 43.00€
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Item number: Cay18861-25
Histamine H2 receptors mediate gastric acid secretion by coupling to Galphas proteins and increasing cAMP formation. Nizatidine is a histamine H2 receptor antagonist that decreases gastric acid secretion (ED50 = 0.9 µM in isolated gastric mucosa of bullfrog and ED50s = 1.383 and 0.08 µmol/kg in rats and dogs,...
Keywords: | LY139037, N'-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N-methyl-2-nitro-1,1-ethenediamine |
Application: | H2-receptor antagonist |
CAS | 76963-41-2 |
MW: | 331.5 D |
From 60.00€
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