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17-phenyl trinor Prostaglandin F2alpha ethyl amide-d4
Item number: Cay316820-25
17-phenyl trinor Prostaglandin F2alpha ethyl amide-d4 is intended for use as an internal standard for the quantification of 17-phenyl trinor prostaglandin F2alpha ethyl amide (Cay-16820) by GC- or LC-MS. 17-phenyl trinor Prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide) is an F-series...
| Keywords: | 17-phenyl trinor PGF2alpha ethyl amide-d4, Bimatoprost-d4,... |
| Application: | Standard |
| MW: | 419.6 D |
From 92.00€
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tetranor-PGFM
Item number: Cay16840-25
tetranor-PGFM is the major urinary metabolite of PGF2alpha. Normal healthy females excrete 7-13 µg of tetranor-PGFM per day compared to 11-59 µg/24 hours for healthy males. In pregnant females, tetranor-PGFM levels in the urine are 2 to 5-fold higher and diminish to pre-pregnancy levels soon after labor.Formal Name:...
| Keywords: | tetranor-Prostaglandin F Metabolite, 9alpha,11alpha-dihydroxy-15-oxo-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid |
| Application: | Bioactive lipid assays |
| CAS | 23109-94-6 |
| MW: | 330.4 D |
From 179.00€
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Guanylyl Imidodiphosphate (lithium salt)
Item number: Cay16880-25
Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and...
| Keywords: | 5'-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt |
| Application: | Nonhydrolyzable GTP analog |
| CAS | 64564-03-0 |
| MW: | 545.9 D |
From 64.00€
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17-phenyl trinor Prostaglandin F2alpha
Item number: Cay16810-25
17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. At the rat recombinant FP receptor expressed...
| Keywords: | 17-phenyl trinor PGF2alpha, Bimatoprost (free acid),... |
| Application: | FP receptor agonist |
| CAS | 38344-08-0 |
| MW: | 388.5 D |
From 77.00€
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R-7050
Item number: Cay16870-25
R-7050 is a cell-permeable antagonist of signaling through the TNF-alpha receptor complex (EC50 = 0.631 µM). It blocks TNF-alpha-induced binding of TNF-alpha receptor I with TNF-alpha receptor-associated death domain protein and receptor interacting protein 1, which, in turn, prevents internalization of the receptor...
| Keywords: | TNF-alpha Antagonist III, 8-chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline |
| Application: | Cell-permeable TNF-alpha receptor complex signaling antagonist |
| CAS | 303997-35-5 |
| MW: | 380.8 D |
From 43.00€
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Leflunomide
Item number: Cay14860-25
Leflunomide is a synthetic isoxazol and a prodrug form of A-771726 (Cay-14404), a dihydroorotate dehydrogenase inhibitor. Leflunomide inhibits de novo pyrimidine synthesis to regulate T lymphocyte progression through the cell cycle. It inhibits proliferation and activation of T cells when used at concentrations of...
| Keywords: | Arava, HW 486, SU 101, 5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide |
| Application: | Immunosuppressant, Pyrimidine synthesis inhibitor, Dihydroorotate dehydrogenase inhibitor |
| CAS | 75706-12-6 |
| MW: | 270.2 D |
From 43.00€
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