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Item number: Cay16178-25

WHI-P154 is a quinazoline derivative that exhibits immunosuppressive effects by selectively inhibiting JAK3 (IC50 = 1.8 µM versus IC50s > 10 µM for JAK1 and JAK2). It has been reported to inhibit additional kinases including EGFR (IC50 = 4 nM) and VEGFR as well as the non-receptor tyrosine kinases, Abl, Lck, and...

Keywords:	JAK3 Inhibitor II, Janus-Associated Kinase 3 Inhibitor II, 2-bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol
Application:	JAK3 inhibitor
CAS	211555-04-3
MW:	376.2 D

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