- Search results for Cay16787-%25
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6 products were found matching "Cay16787-%25"!
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Item number: Cay16786-25
Travoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto fluprostenol isopropyl ester (15-keto travoprost). 15-keto Travoprost is a potential metabolite of travoprost when...
Keywords: | 15-keto Travoprost,... |
Application: | Bioactive lipid assays |
CAS | 404830-45-1 |
MW: | 498.5 D |
From 118.00€
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Item number: Cay16789-25
Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling...
Keywords: | NSC 110364, Urinox, 5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid |
Application: | Antibiotic, Gyrase inhibitor |
CAS | 14698-29-4 |
MW: | 261.2 D |
From 43.00€
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Item number: Cay16707-25
Baricitinib is an inhibitor of JAK1 and JAK2 (IC50s = 0.0059 and 0.0057 µM, respectively). It is selective for JAK1 and JAK2 over JAK3, TYK2, c-Met, and checkpoint kinase 2 (Chk2, IC50s = >0.4, 0.053, >10, and >1 µM, respectively). Baricitinib inhibits IL-6-induced phosphorylation of STAT3 in isolated human...
Keywords: | INCB 028050, LY3009104, 1-(ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile |
Application: | JAK1 / JAK2 inhibitor |
CAS | 1187594-09-7 |
MW: | 371.4 D |
From 50.00€
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Item number: Cay16717-25
Carbonic anhydrases are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to form bicarbonate ion plus a proton. Carbonic anhydrases IX (CAIX) and CAXII are hypoxia and HIF-1-inducible proteins located in cellular transmembranes that regulate intra- and extracellular pH under hypoxic...
Keywords: | NSC 213841, 4-[[[(4-fluorophenyl)amino]carbonyl]amino]-benzenesulfonamide |
Application: | CAIX / CAXII inhibitor |
CAS | 178606-66-1 |
MW: | 309.3 D |
From 65.00€
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Item number: Cay16727-25
Tideglusib is a thiadiazolidinone that prevents inflammation and neurodegeneration when injected into rat hippocampus concurrently with kainic acid, a compound that causes excitotoxicity. Tideglusib-induced neuroprotection, in this model, is attenuated by the PPARgamma antagonist GW9662 (Cay-70785). Interestingly,...
Keywords: | NP031112, 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
Application: | Neuroprotective, GSK3beta inhibitor |
CAS | 865854-05-3 |
MW: | 334.4 D |
From 44.00€
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Item number: Cay18677-25
5-methyl Chrysene is a carcinogenic polycyclic aromatic hydrocarbon consisting of four fused rings and acts as an aryl hydrocarbon receptor agonist. It is produced by the incomplete combustion of organic matter and found primarily in gasoline exhaust and tobacco smoke. 5-methyl Chrysene can be activated to mutagenic...
Keywords: | NSC 407620, 5-methyl-chrysene |
Application: | AH receptor agonist |
CAS | 3697-24-3 |
MW: | 242.3 D |
From 205.00€
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