- Search results for Cay16782-%25
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11 products were found matching "Cay16782-%25"!
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Item number: Cay16786-25
15-keto Fluprostenol isopropyl ester is an ester derivative of the FP receptor agonist fluprostenol (Cay-16768) that is oxidized at carbon 15. It is a potential inactive metabolite of fluprostenol isopropyl ester (travoprost, Cay-16769) based on the published metabolism of latanoprost (Cay-16812) by...
Keywords: | 15-keto Travoprost,... |
Application: | Bioactive lipid assays |
CAS | 404830-45-1 |
MW: | 498.5 D |
From 118.00€
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Item number: Cay16780-25
2,3-dinor Fluprostenol is a derivative of the FP receptor agonist and prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020) analog fluprostenol (Cay-16768).Formal Name: (+)-9alpha,11alpha,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-2,3,17,18,19,20-hexanor-prosta-5Z,13E-dien-1-oic acid. Molecular Formula:...
Keywords: | (+)-9alpha,11alpha,15R-trihydroxy-16-(3-(trifluoromethyl)phenoxy)-2,3,17,18,19,20-hexanor-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
MW: | 430.4 D |
From 158.00€
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Item number: Cay16758-25
Nonsense mutations create a premature termination of mRNA translation and have been implicated in various genetic disorders, including muscular dystrophy and cystic fibrosis. PTC-124 is a nonaminoglycoside that has been reported to selectively induce ribosomes to read through premature nonsense stop signals on mRNA,...
Keywords: | Ataluren, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-benzoic acid |
Application: | Nonsense codon suppressor |
CAS | 775304-57-9 |
MW: | 284.3 D |
From 66.00€
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Item number: Cay16768-25
Fluprostenol is a metabolically stable analog of PGF2alpha with potent FP receptor agonist activity. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol inhibits PGF2alpha binding to human and rat FP receptors with IC50...
Keywords: | 16-m-trifluoromethylphenoxy tetranor Prostaglandin F2alpha,... |
Application: | FP receptor agonist |
CAS | 54276-17-4 |
MW: | 458.5 D |
From 86.00€
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Item number: Cay16708-25
SR 3677 is a potent, ATP-competitive inhibitor of Rho-associated kinases (ROCKs) that shows greater potency against ROCK2 than ROCK1 in enzyme and cell-based assays (IC50 values are 3 and 56 nM, respectively). At 3 µM, SR 3677 inhibits only 5 (Akt3, Clk1, Clk2, Clk4, Lats2) out of 353 kinases with greater than 50%...
Keywords: | N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide |
Application: | ROCK inhibitor |
CAS | 1072959-67-1 |
MW: | 408.5 D |
From 60.00€
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Item number: Cay16287-25
TDZD-8 is a thiadiazolidine derivative that acts as a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3beta (GSK3beta, IC50 = 2 µM), binding to the active site of GSK3beta. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase,...
Keywords: | GSK3beta Inhibitor I, NP 01139, 2-methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
Application: | GSK3-beta inhibitor |
CAS | 327036-89-5 |
MW: | 222.3 D |
From 82.00€
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Item number: Cay16987-25
Cryptotanshinone is a natural quinoid diterpene first isolated from Salvia miltiorrhiza roots, which are used in traditional Chinese medicine for a variety of conditions. Cryptotanshinone, at 10-20 µM, stimulates AMP-activated protein kinase in C2C12 myotubes and activates p38 MAPK in DU145 cells. It inhibits the...
Keywords: | (1R)-1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-phenanthro[1,2-b]furan-10,11-dione |
Application: | Apoptosis inducer |
CAS | 35825-57-1 |
MW: | 296.4 D |
From 43.00€
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Item number: Cay16087-25
Clomiphene is a selective estrogen receptor modulator that impairs the activation of estrogen receptors (ERs) by 17beta-estradiol. It potently binds both ERalpha and ERbeta (Ki = 0.9 and 1.2 nM, respectively). Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of...
Keywords: | Clomifene, NSC 35770, Omifin, 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-ethanamine... |
Application: | Selective estrogen receptor modulator |
CAS | 50-41-9 |
MW: | 598.1 D |
From 43.00€
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Item number: Cay16827-25
N-undecanoyl-L-Homoserine lactone is a bacterial quorum-sensing signaling molecule. It induces GFP production in an E. coli reporter strain expressing the V. fischeri LuxR-PluxI quorum-sensing operon when used at concentrations ranging from 100 to 1,000 nM. N-undecanoyl-L-Homoserine lactone also inhibits the...
Keywords: | C11-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-undecanamide |
Application: | Bioactive lipid assays |
CAS | 216596-71-3 |
MW: | 269.4 D |
From 60.00€
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Item number: Cay18768-25
Ivermectin B1a is the main component (>80%) of the anthelmintic ivermectin, which also contains ivermectin B1b (23824). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very...
Keywords: | 22,23-dihydro Avermectin B1a, 5-O-demethyl-22,23-dihydro-avermectin A1a |
Application: | Antiparasitic, Anthelmintic |
CAS | 71827-03-7 |
MW: | 875.1 D |
From 171.00€
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Item number: Cay17862-25
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is a deaminated sialic acid that was first...
Keywords: | Deaminoneuraminic acid, KDN, Ketodeoxynonulosonic acid, 3-deoxy-D-glycero-D-galacto-2-nonulopyranosonic acid |
Application: | Deaminated sialic acid |
CAS | 153666-19-4 |
MW: | 268.2 D |
From 61.00€
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