10 products were found matching "Cay16781"!

9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2alpha and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol....

Activation of bone morphogenetic protein (BMP) type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the nucleus to induce transcriptional activation important for normal development and tissue repair. K02288 is a 2-aminopyridine-based...

Adenosine 5'-diphosphate (ADP) is a central component of energy storage, metabolism, and signal transduction in vivo. It serves as a precursor for ATP (Cay-14498) and, in this capacity, is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division. ADP...

15(S)-Fluprostenol isopropyl ester is an isomer of the prostaglandin F2alpha analog fluprostenol isopropyl ester (Cay-16769). It is a potential prodrug to 15(S)-fluprostenol (Cay-16787), which could act as an agonist at FP receptors albeit at a lower potency than 15(R) epimer and FP receptor agonist fluprostenol...

9-keto Fluprostenol isopropyl ester is an ester derivative of the FP receptor agonist fluprostenol (Cay-16768) that is oxidized at carbon 9. It is a potential prodrug to 9-keto fluprostenol (Cay-16781), which could act as an agonist at EP receptors. It is also a potential metabolite of fluprostenol isopropyl ester...

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling...

15-keto Fluprostenol isopropyl ester is an ester derivative of the FP receptor agonist fluprostenol (Cay-16768) that is oxidized at carbon 15. It is a potential inactive metabolite of fluprostenol isopropyl ester (travoprost, Cay-16769) based on the published metabolism of latanoprost (Cay-16812) by...

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2alpha and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto...

15(S)-Fluprostenol is an isomer of the FP receptor agonist fluprostenol (Cay-16768). It is a potential active metabolite of 15(S)-fluprostenol isopropyl ester (Cay-16788), which could act as an agonist at FP receptors albeit at a lower potency than the 15(R) epimer fluprostenol.Formal Name:...

15-keto Fluprostenol is a derivative of the FP receptor agonist fluprostenol (Cay-16768) that is oxidized at carbon 15. It is a potential inactive metabolite of 15-keto fluprostenol isopropyl ester (Cay-16786). It is also a potential metabolite of fluprostenol based on the published metabolism of latanoprost...