10 products were found matching "Cay16765"!

(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent...

The two isoforms of glycogen synthase kinase 3, GSK3alpha and GSK3beta, constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer's disease and osteogenesis. AZD 1080 is a potent, brain permeable inhibitor of...

(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol. (+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of...

5-trans Fluprostenol is a potential impurity in commercial preparations of the FP receptor agonist fluprostenol (Cay-16768).Formal Name: [1R-[1alpha(E),2beta(1E,3R*),3alpha,5alpha]]-7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid. CAS Number: 57968-83-9. Synonyms:...

Creatinine-d3 is intended for use as an internal standard for the quantification of creatinine (Cay-31164) by GC- or LC-MS. Creatinine is synthesized in kidney, liver, and pancreas and transported in blood to muscle and brain where it is phosphorylated to phosphocreatine. Some free creatine in muscle is converted to...

Fluprostenol is a metabolically stable analog of PGF2alpha with potent FP receptor agonist activity. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol inhibits PGF2alpha binding to human and rat FP receptors with IC50...

16-phenoxy tetranor Prostaglandin F2alpha (16-phenoxy tetranor PGF2alpha) is a metabolically stable analog of PGF2alpha. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2alpha.Formal Name:...

AS-1842856 is a potent inhibitor of forkhead box class O transcription factor 1 (FoxO1, IC50 = 33 nM in HepG2 cells). Inhibition of FoxO1-mediated transactivation with AS-1842856 leads to a dose-dependent decrease in expression of glucose-6 phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) mRNA and...

Fluprostenol isopropyl ester is an analog of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020) and an isopropyl ester prodrug form of (+)-fluprostenol (Cay-16768). Fluprostenol isopropyl ester is an FP receptor agonist, inducing phosphoinositide turnover in HEK293 cells expressing the human ocular FP receptor...

(±)-Cloprostenol (sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid. Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha, Cay-16010). It is 200 times and 100 times more potent than PGF2alpha in terminating pregnancy in hamsters and rats, respectively, without...