- Search results for Cay16720
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9 products were found matching "Cay16720"!
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Item number: Cay16720-1
15-keto Prostaglandin F2alpha (15-keto PGF2alpha) is the first metabolite of PGF2alpha. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone. 15-keto PGF2alpha stimulates the male goldfish and salmon olfactory receptors with detection...
Keywords: | 15-keto PGF2alpha, 9alpha,11alpha-dihydroxy-15-oxo-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 35850-13-6 |
MW: | 352.5 D |
From 98.00€
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Item number: Cay16724-10
Phenylacetyl L-glutamine is an end product of phenylalanine metabolism in humans and primates. In a large number of other mammals, the corresponding end product is phenylacetylglycine. Phenylacetyl L-glutamine is excreted in urine, with urinary concentrations increasing with age.Formal Name:...
Keywords: | NSC 203800, PAG, N2-(2-phenylacetyl)-L-glutamine |
Application: | Phenylalanine metabolism end product |
CAS | 28047-15-6 |
MW: | 264.3 D |
From 66.00€
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Item number: Cay16727-10
Tideglusib is a thiadiazolidinone that prevents inflammation and neurodegeneration when injected into rat hippocampus concurrently with kainic acid, a compound that causes excitotoxicity. Tideglusib-induced neuroprotection, in this model, is attenuated by the PPARgamma antagonist GW9662 (Cay-70785). Interestingly,...
Keywords: | NP031112, 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
Application: | Neuroprotective, GSK3beta inhibitor |
CAS | 865854-05-3 |
MW: | 334.4 D |
From 44.00€
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Item number: Cay16723-10
Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor that is cleaved by serine proteases, resulting in self-activation of the receptor by a tethered ligand. The ligand corresponds to residues 39-44 (SLIGRL in mouse PAR-2). SLIGRL-NH2 is a recombinant peptide that activates PAR2 (EC50 = ~5 µM),...
Keywords: | L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-Leucinamide, trifluoroacetate salt |
Application: | PAR-2 activator |
MW: | 656.8 D |
From 50.00€
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Item number: Cay16726-10
Sotrastaurin is a protein kinase C (PKC) inhibitor that displays immunosuppressive activity, blocking T cell activation through the disruption of downstream NF-kappaB signaling. In cell-free assays, sotrastaurin was reported to inhibit PKCalpha, betaI, delta, epsilon, eta, and theta with Ki values of 0.95, 0.64,...
Keywords: | AEB071, 3-(1H-indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor, Immunosuppressor |
CAS | 425637-18-9 |
MW: | 438.5 D |
From 66.00€
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Item number: Cay16722-50
Fudosteine is a cysteine derivative that interferes with the increase in goblet cell number, expression of the mucin MUC5AC, and subsequent mucin secretion, in airways agonized with tobacco smoke, isoproterenol, lipopolysaccharide, TNF-alpha, or oxidants. Fudosteine, which is a thiol compound with antioxidant...
Keywords: | SS320A, S-(3-hydroxypropyl)-L-cysteine |
Application: | Cysteine derivative |
CAS | 13189-98-5 |
MW: | 179.2 D |
From 43.00€
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Item number: Cay16729-10
ZM 39923 is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 µM, respectively). In the absence of the reducing agent dithiothreitol, ZM 39923 also inhibits human tissue transglutaminase 2 (TGM2) and the...
Keywords: | JAK3 Inhibitor IV, Janus-Associated Kinase 3 Inhibitor IV,... |
Application: | JAK3 inhibitor |
CAS | 1021868-92-7 |
MW: | 367.9 D |
From 60.00€
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Item number: Cay16728-10
Glycogen synthase kinase 3beta (GSK3beta) was originally identified for its ability to constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. It can also phosphorylate proteins that are relevant to osteogenesis and Alzheimer's disease, the latter for which it has earned the...
Keywords: | 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide |
Application: | GSK3beta inhibitor |
CAS | 486424-20-8 |
MW: | 453.5 D |
From 44.00€
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Item number: Cay16725-10
3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARgamma coactivator 1alpha (PGC-1alpha). PGC-1alpha activation results in enhanced expression...
Keywords: | PNU 10483, beta-GPA, N-(aminoiminomethyl)-beta-alanine |
Application: | Creatine analog |
CAS | 353-09-3 |
MW: | 131.1 D |
From 43.00€
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