11 products were found matching "Cay16685"!

Lumula is an ethyl amide derivative of the prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020) analog unoprostone (Cay-16680).Formal Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-N-ethyl-5-heptenamide. CAS Number: 511229-72-4. Synonyms: Maxeyprost, Unoprostone N-ethyl amide. Molecular...

3,4-Methylenedioxycathinone (hydrochloride) (Cay-16688) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.Formal Name: 2-amino-1-(1,3-benzodioxol-5-yl)-1-propanone, monohydrochloride. CAS Number: 38061-37-9. Molecular Formula: C10H11NO3 ....

XLR11 (Cay-11565) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB2 receptor over the central CB1 receptor. XLR11 also has an N-(5-fluoropentyl) chain, which increases binding to both CB receptors. XLR11 N-(4-pentenyl) analog is a...

11-keto-beta-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). Boswellic acids are specific, non-redox inhibitors of leukotriene synthesis via 5-lipoxygenase that demonstrate anti-inflammatory and anti-arthritic...

Pyr3 is a pyrazole compound that selectively antagonizes the transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 µM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05...

The kinesin-like spindle protein Eg5, also known as KSP and Kif11, is a motor protein that is essential for establishing a bipolar spindle during mitosis. Eg5-I is a potent inhibitor of Eg5, both in vitro and in cells (IC50s = 127 and 190 nM, respectively). It is an analog of S-trityl-L-cysteine (STLC), but is more...

Bavachin is a flavonoid first isolated from seeds of P. corylifolia. It is a phytoestrogen that activates the estrogen receptors ERalpha and ERbeta (EC50s = 320 and 680 nM, respectively). Through this action, bavachin stimulates osteoblast proliferation and differentiation and prevents bone loss following...

Evodiamine is a natural indole alkaloid found in the fruits of Wu Zhu Yu, a plant used in traditional Chinese medicine. Studies involving evodiamine have demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions. It can act as an aryl hydrocarbon antagonist (Ki = 28 nM), activator...

Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Cay-16681), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered...

P7C3 is an orally bioavailable and brain penetrant aminopropyl carbazole that exhibits proneurogenic and neuroprotective activity by preventing apoptosis of newly postmitotic neurons in the subgranular zone of the hippocampal dentate gyrus. At doses of 5 mg/kg and above, it has been shown to promote the survival of...

Unoprostone isopropyl ester is an ocular hypotensive agent, a prodrug form of the FP receptor agonist unoprostone (Cay-16680), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It inhibits contractions induced by the peptide vasoconstrictor endothelin-1 (Cay-24127) in isolated porcine...