7 products were found matching "Cay16680"!

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Unoprostone
Unoprostone

Item number: Cay16680-10

Unoprostone is an agonist of FP receptors (EC50 = 4.12 µM), an active metabolite the ocular hypotensive agent unoprostone isopropyl ester (Cay-16681), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It is formed from unoprostone isopropyl ester by hydrolysis. Intravitreal administered...
Keywords: 13,14-dihydro-15-keto-20-ethyl PGF2alpha, 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2alpha,...
Application: Bioactive lipid assays
CAS 120373-36-6
MW: 382.5 D
From 82.00€ *
Review
Guanylyl Imidodiphosphate (lithium salt)
Guanylyl Imidodiphosphate (lithium salt)

Item number: Cay16880-25

Guanylyl imidodiphosphate is a nonhydrolyzable analog of GTP that can bind to and irreversibly activate G proteins in the presence of Mg2+. This nucleotide is a potent stimulator of adenylate cyclase. Guanylyl imidodiphosphate is used in studies of protein synthesis since the process of GTP binding, hydrolysis, and...
Keywords: 5'-guanylic acid, monoanhydride with imidodiphosphoric acid, tetralithium salt
Application: Nonhydrolyzable GTP analog
CAS 64564-03-0
MW: 545.9 D
From 64.00€ *
Review
IPI-145
IPI-145

Item number: Cay16800-10

IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
Keywords: Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone
Application: PI3K gamma / delta inhibitor
CAS 1201438-56-3
MW: 416.9 D
From 92.00€ *
Review
P7C3
P7C3

Item number: Cay16682-50

P7C3 is an orally bioavailable and brain penetrant aminopropyl carbazole that exhibits proneurogenic and neuroprotective activity by preventing apoptosis of newly postmitotic neurons in the subgranular zone of the hippocampal dentate gyrus. At doses of 5 mg/kg and above, it has been shown to promote the survival of...
Keywords: 3,6-dibromo-alpha-[(phenylamino)methyl]-9H-carbazole-9-ethanol
Application: Neuroprotective
CAS 301353-96-8
MW: 474.2 D
From 141.00€ *
Review
Unoprostone isopropyl ester
Unoprostone isopropyl ester

Item number: Cay16681-50

Unoprostone isopropyl ester is an ocular hypotensive agent, a prodrug form of the FP receptor agonist unoprostone (Cay-16680), and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It inhibits contractions induced by the peptide vasoconstrictor endothelin-1 (Cay-24127) in isolated porcine...
Keywords: 13,14-dihydro-15-keto-20-ethyl Prostaglandin F2alpha isopropyl ester, Rescula,...
Application: Bioactive lipid assays
CAS 120373-24-2
MW: 424.6 D
From 77.00€ *
Review
Anti-EP2 Receptor:SureLight(TM) R-PE
Anti-EP2 Receptor:SureLight(TM) R-PE

Item number: Cay16684-50

Anti-EP2 (Prostaglandin E2) Receptor conjugated to SureLight(TM) R-PE Antibody: Rabbit anti-EP2 (Prostaglandin E2) Receptor Reactivity: Reactive with human, murine, and rat EP2 receptors (other species not tested), Not reactive with EP1, EP3, and EP4 receptors. Uses: Flow cytometry, fluorescence-activated cell...
Keywords: Anti-PTGER2, Anti-Prostanoid EP2 receptor, Anti-PGE receptor EP2 subtype, Anti-PGE2 receptor EP2 subtype,...
Application: FC, Cell-Based Assays, Microarrays, Microplate
Host: Rabbit
Species reactivity: human, mouse, rat
559.00€ *
Review
Anti-EP4 Receptor (C-Term):SureLight(TM) R-PE
Anti-EP4 Receptor (C-Term):SureLight(TM) R-PE

Item number: Cay16687-50

Anti-EP4 (Prostaglandin E4) Receptor (C-Term) conjugated to SureLight(TM) R-PE Antibody: Rabbit anti-EP4 Receptor (C-Term) IgG Reactivity: Human, murine, rat, and ovine EP4 receptor, non-reactive with EP1, EP2, and EP3 receptors, other species not tested. Uses: Flow cytometry and fluorescence-activated cell...
Keywords: Anti-PTGER2, Anti-PTGER4, Anti-Prostanoid EP4 receptor, Anti-PGE receptor EP4 subtype, Anti-PGE2 receptor EP4 subtype,...
Application: FC, Cell-Based Assays
Host: Rabbit
Species reactivity: human, mouse, rat, sheep
559.00€ *
Review