- Search results for Cay16660
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11 products were found matching "Cay16660"!
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Item number: Cay16660-1
13,14-dihydro Prostaglandin F2alpha (13,14-dihydro PGF2alpha) is the analog of PGF2alpha which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2alpha. The ED50 value for 13,14-dihydro PGF2alpha as a luteolytic agent in hamsters is 1.5 µg/100...
Keywords: | 13,14-dihydro PGF2alpha, 9alpha,11alpha,15S-trihydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 27376-74-5 |
MW: | 356.5 D |
From 66.00€
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Item number: Cay11160-10
D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans. D2PM is also used in organic synthesis to prepare the Corey-Bakshi-Shibata catalyst. This product is intended for forensic purposes.Formal Name: alpha,alpha-diphenyl-2R-pyrrolidinemethanol,...
Keywords: | Diphenyl-2-pyrrolidinemethanol, Diphenylprolinol, alpha,alpha-diphenyl-2R-pyrrolidinemethanol, monohydrochloride |
Application: | Analytical reference standard, psychoactive designer drug, Corey-Bakshi-Shibata catalyst synthesis |
CAS | 172152-19-1 |
MW: | 289.8 D |
From 84.00€
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Item number: Cay11600-10
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
Keywords: | GNE-0941, Pictilisib, Pictrelisib,... |
Application: | PI3K inhibitor |
CAS | 957054-30-7 |
MW: | 513.6 D |
From 180.00€
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Item number: Cay16000-5
Fosmidomycin is an antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces that inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Fosmidomycin is active against both Gram-negative and Gram-positive bacteria and the human malarial...
Keywords: | Antibiotic FR31564, FR31564, P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt |
Application: | Antibiotic, DOXP reductoisomerase inhibitor |
CAS | 66508-37-0 |
MW: | 205.1 D |
From 60.00€
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Item number: Cay11660-100
Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35%...
Keywords: | AL 4862, 4R-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-1,1-dioxide-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide |
Application: | Carbonic anhydrases inhibitor |
CAS | 138890-62-7 |
MW: | 383.5 D |
From 44.00€
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Item number: Cay16665-50
Melphalan is a phenylalanine derivative of mechlorethamine, belonging to the family of nitrogen mustard alkylating agents that are used for chemotherapy. It attaches an alkyl group to guanine bases in DNA at the 7-nitrogen of the imidazole ring, which leads to DNA interstrand and intrastrand crosslinks,...
Keywords: | Alanine Nitrogen Mustard, Alkeran, L-Phenylalanine Mustard, NSC 241286, NSC 8806, 4-[bis(2-chloroethyl)amino]-L-phenylalanine |
Application: | Alkylating agent |
CAS | 148-82-3 |
MW: | 305.2 D |
From 109.00€
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Item number: Cay16666-50
Monocrotaline is a natural 11-membered macrocyclic pyrrolizidine alkaloid used in an animal model of pulmonary hypertension. It is metabolized by cytochrome P450 3A4 in the liver to monocrotaline pyrrole. Administration of monocrotaline or its metabolite monocrotaline pyrrole to rats causes progressive lung injury...
Keywords: | Crotaline, MCT, NSC 28693,... |
Application: | Pulmonary hypertension inducer |
CAS | 315-22-0 |
MW: | 325.4 D |
From 84.00€
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Item number: Cay16667-10
BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
Keywords: | IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate) |
Application: | Cell permeable IKK-alpha/beta inhibitor |
CAS | 547757-23-3 |
MW: | 291.8 D |
From 60.00€
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Item number: Cay16669-10
2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae. Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to...
Keywords: | 5-FAA, 5-Fluoroanthranilic Acid, NSC 513308, 2-amino-5-fluoro-benzoic acid |
Application: | Positive TRP1 yeast genetic marker selection |
CAS | 446-08-2 |
MW: | 155.1 D |
From 66.00€
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Item number: Cay16664-50
Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: | OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,... |
Application: | Arginine vasopressin receptor 2 (AVPR2) antagonist |
CAS | 138470-70-9 |
MW: | 464 D |
From 48.00€
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Item number: Cay16668-10
The kinesin-like spindle protein Eg5, also known as KSP and Kif11, is a motor protein that is essential for establishing a bipolar spindle during mitosis. Eg5-I is a potent inhibitor of Eg5, both in vitro and in cells (IC50s = 127 and 190 nM, respectively). It is an analog of S-trityl-L-cysteine (STLC), but is more...
Keywords: | (2R)-2-amino-3-[[(4-methoxyphenyl)diphenylmethyl]thio]-1-propanol |
Application: | Eg5 inhibitor |
CAS | 1338701-15-7 |
MW: | 379.5 D |
From 66.00€
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