- Search results for Cay16450
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5 products were found matching "Cay16450"!
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Item number: Cay16450-1
U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist. It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0,...
Keywords: | 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha, 9,11-dideoxy-9alpha,11alpha-methanoepoxy Prostaglandin F2alpha,... |
Application: | TP receptor agonist |
CAS | 56985-40-1 |
MW: | 350.5 D |
From 130.00€
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Item number: Cay11164-50
5-Azacytidine, a chemical analogue of the DNA and RNA nucleoside cytidine, is an inhibitor of DNA methyltransferases, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 µM for in vitro anti-myeloma...
Keywords: | 5-AzaC, Antibiotic U 18496, Ladakamycin, Mylosar, NSC 102816, NSC 103-627, U 18496, WR 183027,... |
Application: | DNA methyltransferase inhibitor |
CAS | 320-67-2 |
MW: | 244.2 D |
From 27.00€
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Item number: Cay16644-50
Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. Wnt-C59 is a potent inhibitor of PORCN, as measured by prevention of Wnt3A...
Keywords: | PORCN Inhibitor II, 4-(2-methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]-benzeneacetamide |
Application: | Porcupine inhibitor |
CAS | 1243243-89-1 |
MW: | 379.5 D |
From 60.00€
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Item number: Cay11664-500
Forskolin (Cay-11018) is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate,...
Keywords: | (3R,4aS,5S,6S,6aS,10aS,10bR)-5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-... |
Application: | Adenylate cyclase binding |
CAS | 64657-18-7 |
MW: | 378.5 D |
From 77.00€
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Item number: Cay16664-50
Mozavaptan is an orally bioavailable antagonist of vasopressin V2 receptors (Ki = 9.42 nM in HeLa cells expressing the human receptor). It is selective for vasopressin V2 over V1 receptors (IC50s = 14 and 1,200 nM, respectively) in radioligand binding assays using rat kidney and rat liver membranes that endogenously...
Keywords: | OPC 31260, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl-benzamide,... |
Application: | Arginine vasopressin receptor 2 (AVPR2) antagonist |
CAS | 138470-70-9 |
MW: | 464 D |
From 48.00€
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